Extendin-4 Introduction
Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and chemical trading company headquartered in Xi'an, Shaanxi Province, China. Founded in 2018, the company focuses on providing pharmaceutical intermediates, plant extracts, food additives, and feed ingredients to the global B2B market.
As a lean, professional supplier, we implement rigorous quality control to ensure batch stability and compliance. With an experienced international sales team, we offer highly competitive prices, reliable delivery times, and one-stop export services.
Our products are widely supplied to the pharmaceutical, health supplement, cosmetic, and feed industries in Europe, North America, Southeast Asia, and the Middle East.
The amino acid sequence of Exenatide acetate partially overlaps with a portion of human GLP-1. Extendin-4 has been shown in vitro to be able to bind and activate the known human GLP-1 receptor. This means that by including cAMP or other intracellular signaling mechanisms, the production of insulin dependent on glucose and the secretion of insulin by pancreatic β cells in the body can be increased. Its CAS number: 141732-76-5; molecular formula: C186H286N50O62S; molecular weight: 4244.60796; EINECS number: 1592732-453-0
What is the mechanism of action of Extendin-4?
Exenatide-4 is an artificially synthesized GLP-1 receptor agonist that can replicate the multiple glucose-regulating effects of natural GLP-1. This substance can bind to the GLP-1 receptors of pancreatic β cells. When blood sugar levels rise in the body, it promotes the release of INSULIN and reduces excessive secretion of glucagon, as well as lowers the total amount of glucose produced by the liver. In addition, Exenatide acetate can slow down the rate of gastric emptying, delay the absorption of sugar by the body, and send satiety signals to the brain, thereby reducing the desire to eat. Through the combined action of multiple pathways, it achieves the effects of regulating blood sugar and assisting in weight control.
What is the market outlook for Extendin-4?
As global research on metabolic-related topics continues to gain momentum, the GLP-1 pathway has become a key research focus for various laboratories. Exenatide acetate, as a classic GLP-1 receptor agonist research peptide, has long maintained stable demand. Many research institutions and biotechnology development enterprises use it as a positive control tool to conduct cell and animal experiments related to glucose metabolism, appetite regulation, and fat metabolism.
Compared with the new generation of long-acting GLP-1 peptides, Extendin-4 has a long development history, abundant relevant literature data, and a mature experimental reference system, making it very suitable for use as a reference for mechanism exploration and compound screening. However, there is also market competition pressure. More and more manufacturers are entering the layout of similar peptide synthesis, which will bring price competition in the long term. At the same time, the mainstream commercialized preparations are more inclined towards long-term modified molecules, limiting the large-scale industrialization transformation space of this raw material.
Overall, it is suitable for focusing on the research raw material field and providing stable shipments to university laboratories and CRO research institutions. To achieve greater growth, it is necessary to connect with cutting-edge research projects such as peptide formulation improvement and combined administration.
MF of Extendin-4
| CAS | 141732-76-5 |
| Molecular formula | C186H286N50O62S |
| Molecular weight | 4244.60796 |
| EINECS | 1592732-453-0 |
| Melting point | >209°C |
Specification
| Item | Specification | Result |
| Appearance | White powder | Complies |
| Assay | ≥ 98.0% | 99.17% |
| Conclusion | Conform with enterprise specification | |
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A variety of shipping methods for you to choose
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Exenatide acetate etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
FAQ:
Q1:For which types of diabetic patients is Extendin-4 suitable?
For dynamic neck lines caused by tension in the neck muscles, it has a certain auxiliary relaxation effect. However, most neck lines are of the structural and static type (such as skin relaxation, fat accumulation, and collagen loss), and this ingredient is basically powerless against them.
Q2:What are the most common side effects of Extendin-4?
The most common symptom is nausea, which is related to the dosage. However, the symptoms of most people will alleviate as the treatment duration increases. In addition, other symptoms such as vomiting, diarrhea, loss of appetite, dizziness and reactions at the injection site may also occur.
Q3:Does Exenatide Acetate cause hypoglycemia?
It itself does not pose a high risk of causing hypoglycemia because it only "functions" when blood sugar is high. However, when it is used in combination with sulfonylurea drugs or INSULIN, the risk of hypoglycemia significantly increases, and usually the dosage of sulfonylurea drugs or INSULIN needs to be reduced.
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