Product description

API Tirzepatide Peptide Powder CAS 2023788-19-2 is a novel dual-receptor agonist of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP, also known as gastric inhibitory peptide). Both GLP-1 and GIP belong to the incretin family and are polypeptides secreted by the human gastrointestinal mucosa. GLP-1 binds to receptors on pancreatic islet cells and stimulates insulin secretion, thereby lowering blood sugar. It can also delay gastric emptying and suppress appetite, thus controlling weight. GIP, on the other hand, inhibits gastric acid and pepsin secretion, stimulates insulin release, and inhibits gastric motility and emptying, complementing the effects of GLP-1 receptor agonists.
Tirzepatide integrates the effects of two insulin-stimulating mechanisms into a single molecule, representing a novel product for the treatment of type 2 diabetes.
Tirzepatide and semaglutide have similar sequences. The lys side chain in the sequence is modified with PEG, which is a functional group of the peptide and can increase the water solubility of the sequence.
Tirzepatide, the world's first dual-target incretin agonist, has become a first-line treatment option for type 2 diabetes and obesity due to its multiple advantages, including potent blood glucose lowering, significant weight loss, and cardiovascular and renal protection.

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COA
| Tests | Specifications | Results |
| Appearance | White or almost white powder | White powder |
| Molecular Ion Mass | 4813.45 | Conforms |
| Purity (HPLC) | NLT 98.0% | 99.74% |
| Related substances (HPLC) | Total impurities: NMT 2.0% | 0.83% |
| Maximum single impurity: NMT 1.0% | 0.34% | |
| Acetic acid Content (HPLC) | NMT 15.0% | N.D |
| TFA Content (HPLC) | NMT 1.0% | N.D |
| Water Content (K.F) | NMT 8.0% | 7.43% |
| pH | Reported value(C=5mg/ml) | 8.5 |
| Residue solvents(GC) | Acetonitrile NMT 410ppm | 91ppm |
| Methanol NMT 3000ppm | 26ppm | |
| Methylene chloride NMT 600ppm | N.D | |
| Isopropyl ether NMT 5000ppm | 13ppm | |
| N,N-Dimethylformamide NMT 880ppm | N.D | |
| Oligomer | NMT 3.0% | N.D |
| Bacterial Endotoxins | NMT 10 EU/mg | Conforms |
| Microbial Limits | TAMC NMT 50 cfu/0.1g | Conforms |
| TYMC NMT 50 cfu/0.1g | Conforms | |
| Conclusion | Conform with enterprise specification | |
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Appearance: White powder
Purity (HPLC) ≥ 95.0%
Acetate content 5.0% - 12.0%
Water content ≤ 8.0%
Peptide content ≥ 70.0%
Amino acid composition analysis ≤ ± 10%
Molecular formula: C225H348N48O68
Molecular weight: 4813.45
Mechanism of Action of API Tirzepatide Peptide Powder CAS 2023788-19-2 (Dual-Target Synergistic Effect)
Tirzepatide exerts multiple physiological effects by simultaneously activating two incretin receptors:
Promoting Insulin Secretion: Glucose-dependent stimulation of insulin release; the higher the blood glucose level, the stronger the effect, with a low risk of hypoglycemia.
Inhibiting Glucagon Release: Reduces hepatic glucose production, lowering fasting blood glucose.
Delaying Gastric Emptying: Prolongs the time food remains in the stomach, increasing satiety and reducing food intake.
Regulating the Appetite Center: Acts on the hypothalamus, inhibiting appetite and promoting weight loss.
GIP Receptor Advantage: Greater affinity for GIP receptors than GLP-1 receptors, enhancing metabolic regulation and weight loss effects.
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Package

Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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FAQ
01. What is API Tirzepatide Peptide Powder CAS 2023788-19-2?
02. Does API Tirzepatide Peptide Powder CAS 2023788-19-2 affect your brain?
Then, tirzepatide dramatically alleviated spatial learning and memory impairment, inhibited Aβ accumulation, prevented structural damage, boosted the synthesis of synaptic proteins and increased dendritic spines formation in diabetic hippocampus.
03. What are the negative side effects of API Tirzepatide Peptide Powder CAS 2023788-19-2?
Change in vision.
Dehydration-increased thirst, dry mouth, feeling faint or lightheaded, headache, dark yellow or brown urine.
Fast or irregular heartbeat.
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