Abaloparatide API Powder CAS 247062-33-5

Abaloparatide API powder is a peptide composed of 34 amino acid residues and is a novel parathyroid hormone related peptide (PTHrP) developed by Radius Health. It is a potent selective activator of the PTH-I receptor, which can increase bone mineral content, bone density, and bone strength, promoting bone formation. It was approved for market by the FDA on April 28, 2017. The abaloparatide provided by our company is a product designed through molecular technology. According to relevant clinical usage data, pure abaloparatide can better reduce the incidence of fractures and hypercalcemia. Its effectiveness is much higher than that of Teriparatide acetate.

What is the pharmacological mechanism of Abaloparatide?

Abaloparatide API powder is a synthetic parathyroid hormone-related protein analogue, which can increase bone density and strength by promoting new bone formation. Studies have shown that abaloparatide is a selective activator of parathyroid hormone receptor 1(PTHR1), which can promote bone formation and improve cortical structure by enhancing Gs/cAMP signal transduction and β-arrestin recruitment. In vivo study, it is found that the Abaloparatide peptide powder we provide can significantly increase bone mineral density and bone mineral content, enhance bone strength, and reduce the risk of vertebral and non-vertebral fractures.

How to produce better Abaloparatide?

Abaloparatide is a peptide composed of 34 amino acid residues. The latest publicly available method for preparing Abaloparatide is relatively complex and costly. According to relevant literature, three peptide resin fragments were first synthesized using solid-phase synthesis, and then peptide fragments 2 and 3 were linked to peptide resin fragment 1. However, this method requires a freeze-drying process before the condensation of peptide fragments 2 and 3, and the generation of peptide resin fragments 2 and 3 requires the use of a large amount of expensive 2-CTC resin, resulting in increased production costs. And we used the above production method as a template, referencing the method of molecular segmentation and recombination to further reduce the impurities produced. And the crude Abaloparatide peptide powder was purified using reverse phase high-performance liquid chromatography, and the final product reached over 99.85%.

What is the market prospect of Abaloparatide?

Abaloparatide API powder, as an important drug in the treatment of osteoporosis, has broad market prospects and shows a sustained growth trend. According to the latest market data, the global Abaloparatide market is expected to reach $684 million in 2024 and is projected to grow to $997 million by 2031, with a compound annual growth rate (CAGR) of 5.6%.
In the Chinese market, Abaloparatide raw powder has also shown strong growth momentum. In 2023, the size of the Chinese market is expected to reach approximately 1.5 billion yuan, a year-on-year increase of 18.7%. It is expected to exceed 2 billion yuan by 2025, with a compound annual growth rate of 25%.
We expect that in the next 10 years, it will take advantage of the following advantages to take it to the next level:
1. The aging population is intensifying: The world will see an increase in the elderly population. According to calculations by the World Health Organization, the aging growth rate will reach 14.9% in 2023 and is expected to further rise to 16.2% by 2025. The elderly population is the main patient group of osteoporosis, and the continuously growing patient base provides sustained demand for the market.
2. Increased policy support: The Chinese government continues to promote the development of new quality productivity, especially in the pharmaceutical industry. In recent years, a series of encouraging policies have been introduced, and the National Medical Products Administration (NMPA) has accelerated the approval process for Abaloparatide raw materials, with considerable financial subsidies. Many companies hope to make more breakthroughs in this opportunity.
3.Technological progress and cost optimization: With the continuous improvement of production processes, the production cost of Abaloparatide is gradually decreasing, and the price is showing a stable and slightly decreasing trend. This further enhances the accessibility of the product.
4.In terms of competitive landscape, the market share of the Chinese market has reached 43.75%. And it has formed a situation where national medicine takes the lead and various private enterprises continue to innovate, laying the foundation for its application.

A variety of shipping methods for you to choose

Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Abaloparatide API powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

FAQ:

Q1: How to ensure product quality? Can we conduct a test?
A: We always prioritize quality. From raw material procurement to production extraction, every step undergoes strict testing. All finished products undergo dual inspection by our internal QC/QA department and are certified by authoritative third-party laboratories in China. We sincerely welcome you to conduct independent testing on our products and look forward to your feedback to continuously optimize our quality.
Q2: What transportation methods are available?
A: We provide flexible and reliable global logistics solutions, including international express delivery (DHL, UPS, TNT, FedEx, HKEMS), postal services (EMS, Air China Post), and sea freight. To ensure the safety and smooth customs clearance of goods, we use compliant packaging and declaration that meet the requirements of various countries' customs. In addition, we have overseas warehouses in Germany and California, USA, and some orders can be directly shipped locally to further improve delivery efficiency and stability.
Q3: How long does it usually take for the goods to be delivered?
A: The shipping time depends on your address and the selected method:
Small batch orders: usually delivered within 5-7 working days through express delivery such as DHL, UPS, TNT, FedEx, HKEMS, etc.
Large scale orders: Air freight takes about 5-8 working days; Shipping by sea takes about 20-35 working days.
Overseas warehouse direct delivery: If shipped from warehouses in Germany or California, the delivery time in Europe and North America can be further shortened.
We will provide specific logistics tracking information after you place your order, making it convenient for you to check the status of the goods in real time.

Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.

If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email ：sales6@faithfulbio.com   . Our team is committed to ensuring the complete satisfaction of customers.

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