Product description
Tropine Powder is a chemical compound, specifically a tropane alkaloid, known for its role as an intermediate in the synthesis of various bioactive compounds, including the well-known drug atropine. It's a cyclic alcohol and an amine, with a hydroxyl group attached to the third carbon of its tropane ring structure. Tropine is also referred to as 3-tropanol.
Tropine is a naturally occurring organic compound with the chemical formula C8H15NO. It is a derivative of tropane, a bicyclic ring system, and features a hydroxyl (OH) group attached to the third carbon atom.
Tropine Powder is a crucial precursor in the synthesis of numerous tropane alkaloids, including atropine, scopolamine. These alkaloids have diverse pharmacological effects, including anticholinergic and antimuscarinic actions.
In the past, tropine (and specifically its derivative atropine) has been investigated for potential use in treating conditions like angina pectoris. However, it's now primarily used as a building block for synthesizing other valuable drugs.
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COA
| ltems | Standard | Results |
| Appearance | White to pale yellow cystalline powder | white crystalline powder |
| Purity | ≥98.0%on anhvdrous basis | 99.40% |
| Moisture | ≤1.0%no more than 1.0% | 0.42% |
| impurity | β-Tropine:Not more than 0.3% | 0.15% |
| Tropinone:Not more than 0.3% | 0.05% | |
| Other single maximum impurity:Not more than 0.5% | 0.16% | |
| Total impurities:Not more than 10% | 0.28% | |
| Residue on lgnition | ≤0.1%not more than 0.1% | 0.01% |
| Identification | (HNMR) | conforms |
| Conclusion | Conform with enterprise specification | |
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Density: 1.1±0.1 g/cm ³
Boiling point: 233.0±0.0 °C at 760 mmHg
Melting point: 50-60 °C(lit.
Molecular formula: C8H15NO
Molecular weight: 141.211
Flash point: 112.5±14.5 °C
Precise mass: 141.115356
PSA 23.47000
LogP -0.10
What is the mandelic acid ester of Tropine Powder?
Homatropine, the mandelic acid ester of tropine, is used in ophthalmology to evoke a more rapid and less paralytically effect than atropine.
What is the biosynthesis of Tropine Powder?
Tropane alkaloid biosynthesis in plants begins with the decarboxylation of ornithine and/or arginine by ornithine decarboxylase (ODC) or arginine decarboxylase (ADC) to form the polyamine putrescine. The activities of ODC and ADC are dependent on physiological and developmental conditions and are regulated separately.
What are the side effects of Tropine Powder?
Side Effects of Tropine Powder are Dryness in mouth, Difficulty in urination, Constipation, Blurred vision, Dry skin, Slow heart rate, Photophobia, Dilatation of pupil, Loss of accommodation, Fever, Confusion, Eyelid swelling, Tachycardia, Reduced sweating, Heat intolerance, Skin rash, Dizziness, Skin flushing, Restlessness.
The de novo synthesis of monosaccharides to Tropine Powder was achieved for the first time
α-Tropine and β-Tropine, which have opposite three-dimensional structure specificity, as important platform compounds, are the core building blocks in the biosynthesis and chemical synthesis of (down-tropine) alkaloids. However, at present, the supply of α-Tropine and β-Tropine still heavily relies on the extraction from plants or chemical synthesis, which hinders the creation and application of downstream derivatives. The rapid development of synthetic biology helps solve these problems. Based on synthetic biology strategies, microbial cell factories can be constructed to synthesize various high-value-added compounds.
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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