what is Palmitoylethanolamide PEA powder?
Palmitoylethanolamide PEA powder is an endogenous fatty acid amide, and lipid modulator.A main target of PEA is proposed to be the peroxisome proliferator-activated receptor alpha (PPAR-α).PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119. PEA cannot strictly be considered a classic endocannabinoid because it lacks affinity for the cannabinoid receptors CB1 and CB2.
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Product name |
Palmitoylethanolamide PEA |
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CAS |
544-31-0 |
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|
Molecular formula |
C18H37NO2 | |
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Molecular weight |
299.49 | |
| EINECS | 208-867-9 | |
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Appearance |
white powder |
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| Melting point | 97-98℃ | |
| Density | 0.910±0.06 g/cm3(Predicted) |
what is the natural sources of Palmitoylethanolamide PEA powder?
Palmitoylethanolamide PEA is produced in the body and also found in foods like egg yolks, soybeans, peanuts and corns
What is the Key Aspects of Palmitoylethanolamide PEA powder?
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Palmitoylethanolamide PEA powder has shown promise in managing chronic pain conditions and inflammatory responses. Neuroprotective Properties: Research suggests PEA may play a role in protecting nerve cells, potentially impacting neurodegenerative diseases. Endocannabinoid System: PEA interacts with the endocannabinoid system, a network of receptors and molecules involved in regulating various bodily functions. |
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Product Specification
| Items | Specifications |
Result |
|
Appearance |
white powder |
white powder |
|
Assay |
99.0% min |
99.1% |
|
Identification |
Conforms to structure |
Conforms |
| Water Determination | 2% max | 0.4% |
| Residue on ignition | 1% max | 0.2% |
| Loss on drying | 0.5%max | 0.1% |
how about the studies of Palmitoylethanolamide PEA powder?
In vitro research
PEA can effectively prevent mouse cerebellar granule cells from being poisoned by L-Glutamic acid and enhance the motility of microglia. PEA also has a protective effect, such as reducing the formation of propanedial in cells treated with L-buthionine - (S, R) - sulfoximine, which leads to Glutathione deficiency. The effect of PEA can be partially inhibited by finasteride (5a reductase inhibitor)
In vivo research
Palmitoylethanolamide PEA powder reduces the inflammatory response in wild-type mice, but has no effect on PPAR - α deficient mice. PEA can inhibit peripheral inflammation, degranulation of mast cells, and exert neuroprotective and analgesic effects in mice and rats. At the same time, there were changes in the generation of NO, the influx of neutrophils, and the expression of pro-inflammatory proteins such as inducible nitric oxide synthase and cyclooxygenase-2. In addition, PEA can regulate many physiological processes, including pain perception, seizures, and neurotoxicity.
How and where to Buy Palmitoylethanolamide PEA powder?
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A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
|
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
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