Tofacitinib Citrate Powder CAS 540737-29-9
Product Name:Tofacitinib citrate
Synonym:Xeljanz;CP-690550;CP 690500-10;CP 690550-10;(3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3-propanetricarboxylate
CAS NO.:540737-29-9
EINECS NO.:638-826-4
Molecular Formula:C16H20N6O.C6H8O7
Purity & Grade: 99% HPLC; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 25g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months
Description
Products Description
Tofacitinib Citrate Powder is used to treat adults with moderate to severe active rheumatoid arthritis (RA), active psoriatic arthritis, ankylosing spondylitis, moderate to severe ulcerative colitis, and children ages 2 and older with active polyarticular juvenile idiopathic arthritis.
The most common adverse reactions of Tofacitinib citrate are upper respiratory tract infection, headache, diarrhea, nasal congestion, sore throat and nasopharyngitis.
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COA
| ltems | Standard | Results |
| Characteristics | White crystalline powder | Conforms |
| Identification A | IR, UV conform | Conforms |
| Identification B | Should conform | Conforms |
| PH Value | Between 3.9 to 7.1 | 5.3 |
| Water | Between 5.7%~6.8% | 6.5 |
| Heavy metals | Not more than 0.002% | <0.001% |
| Chlorides | Not more than 0.018% | 0.00% |
| Melting range | Between 48.5°C and 52°C | 49.2°C ~50.4°C |
| Bacterial endotoxin | Not more than 0.2 | Conforms |
| Sterility test | Meet the requirements | Conforms |
| Limit of Propanolamine | ≤0.025% | Conforms |
| Limit of Phosphate | ≤0.01% | Conforms |
| Residual solvents | Alcohol: not more than 0.5% | 100ppm |
| Conclusion | Conform with the enterprise standard | |
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What is the mechanism of action of tofacitinib citrate?
Tofacitinib Citrate Powder, is a type of drug known as a Janus kinase (JAK) inhibitor. It works by blocking the action of Janus kinase enzymes, which are involved in the inflammation that causes the symptoms of rheumatoid arthritis and psoriatic arthritis. Tofacitinib is a long-term treatment.
What is the classification of tofacitinib citrate?
Inhibitor and an antirheumatic drug. It contains a tofacitinib. Tofacitinib Citrate is the citrate salt form of tofacitinib, a bioavailable inhibitor of Janus kinases (JAK), with immunomodulatory and anti-inflammatory activities.
What is tofacitinib citrate for ulcerative colitis?
Tofacitinib is the first IBD therapy with rapid onset of action, reducing symptoms as early as 3 days, and thus may have a role in patients who have failed first-line therapy for acute moderate-to-severe UC.
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why choose us
We adhere to the principle of "customer first, honesty first", and always provide customers with high-quality and efficient products and high-quality services. Choose faithfulness. Choose a healthy life!
With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.
Our Factory
Package
Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales4@faithfulbio.com
Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
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