Rivastigmine Tartrate Powder CAS 129101-54-8
Product Name:Rivastigmine tartrate powder;Rivastigmine tartrate
CAS NO.:129101-54-8
Molecular Formula:C18H28N2O8
Purity & Grade: 99% HPLC; Medicine grade
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 24 months
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
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Description
Product Introduction
Rivastigmine tartrate powder is a white to beige solid. Rivastigmine is a physostigmine derivative with a phenyl carbamate structure in its molecule. It is an aminoacid brain-selective cholinesterase inhibitor.It can inhibit both acetylcholinesterase and butyrylcholinesterase, and promote cholinergic nerve conduction by delaying the degradation of released acetylcholine by cholinergic neurons.
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| Rivastigmine tartrate powder Picture | Rivastigmine tartrate powder MF |
Product Application
Rivastigmine tartrate powder can improve cholinergic-mediated cognitive dysfunction, thereby improving the cognitive function of patients with Alzheimer's disease. Rivastigmine has a weak plasma protein binding ability, easily passes through the blood-brain barrier, and has a high degree of brain selectivity. It can not only selectively act on the cerebral cortex and hippocampus areas that are most susceptible to involvement, but also preferentially inhibit the dominant subtype of AChE in the brain, which can reduce peripheral cholinergic side effects while producing therapeutic effects. Rivastigmine tartrate has a short half-life in the body and a long duration of action.
The objective of this study was to develop and validate a method for quantitative analysis of rivastigmine hydrogen tartrate (RHT) in dual-ligand polymeric nanoparticle formulation matrices, drug release medium, and cellular transport medium. An isocratic HPLC analysis method using a reverse phase C18 column and a simple mobile phase without buffer was developed, optimised, and fully validated. Analyses were carried out at a flow rate of 1.5 mL/min at 50°C and monitored at 214 nm.
This HPLC method exhibited good linearity, accuracy, and selectivity. The recovery (accuracy) of RHT from all matrices was greater than 99.2%. The RHT peak detected in the samples of a forced degradation study, drug loading study, release study, and cellular transport study was pure and free of matrix interference. The limit of detection (LOD) and limit of quantification (LOQ) of the assay were 60 ng/mL and 201 ng/mL, respectively. The method was rugged with good intra- and interday precision. This stability indicating HPLC method was selective, accurate, and precise for analysing RHT loading and its stability in nanoparticle formulation, RHT release, and cell transport medium.
Product Specification
| Specification | Requirements | Test Results |
| Appearance | White Powder | White Powder |
| Assay | ≥99.0% | 99.13% |
| Loss On Drying | ≤1.0% | 0.29% |
| Residue On Ignition | ≤0.2% | 0.08% |
| Heavy Metals | ≤20ppm | <10ppm |
| Total Plate Count | ≤100cfu/G | Conform |
| Yeast & Mold | ≤100cfu/G | Conform |
| E.Coli | Negative | Conform |
| Conclusion：Conform with enterprise specification . | ||
How To Obtain Samples Rivastigmine tartrate powder?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the Rivastigmine tartrate powder.
The Best Rivastigmine tartrate powder Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Rivastigmine tartrate powder?
Faithfulbio specialize in Rivastigmine tartrate powder for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
kindly note: Use Rivastigmine tartrate powder for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Rivastigmine tartrate powder?
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