Choline Glycerophosphate Cas 28319-77-9
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Choline Glycerophosphate Cas 28319-77-9

Choline Glycerophosphate Cas 28319-77-9

Product Name:Choline glycerophosphate
Synonym:L-α-Glycerophosphocholine;α-GPC;Choline Alfoscerate;cholini alfosceras;sn-Glycero-3-phosphocholine;alfoscerate de choline;L-a-GPC
CAS NO.:28319-77-9
EINECS NO.:248-962-2
Molecular Formula:C8H20NO6P
Purity & Grade: 99%; Medicine grade
Character:White Powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months

Description

 
 

Product description

NootropicsCholine glycerophosphate

Choline glycerophosphate(GPC) is a water-soluble small molecule substance that exists normally in the human body and is the biosynthetic precursor of the important neurotransmitter Acetylcholine. The most important role of GPC lies in the fact that the choline it produces is a water-soluble B vitamin, which plays a significant role in the brain and nervous system. Research shows that GPC is crucial for the production of certain hormones and neurotransmitters such as Acetylcholine, thereby supporting the functions of the brain and nervous system.

Choline glycerophosphate is not only one of the main osmotic substances of renal medullary cells, but also can parallently change the concentration of osmotic substances inside and outside the cells. This is beneficial for the health of cerebral blood vessels, especially for behavioral and emotional disorders caused by brain decline. Choline glycerophosphate has the potential to treat and prevent a variety of biochemical lesions. Researchers have found that it can alter the structure of phosphate lipid compounds in the membranes of neurons, and have discovered that it has a peculiar effect in relieving physical tension among the related factors that cause neurodegenerative syndrome.

Choline glycerophosphate is an intermediate of phospholipid metabolism that exists naturally in the human body. It is present in cells and throughout the human body. Structurally, it is composed of choline, glycerol and phosphoric acid. It is a major preservation form of choline and is recognized as a source of choline. Because it is an endogenous substance, its toxic and side effects are extremely low. After absorption, Choline glycerophosphate is decomposed into choline and glycerophosphate under the action of enzymes in the body. Among them, choline participates in the biosynthesis of acetylcholine, which is a kind of neurotrigger neurotransmitter. Glycerophosphate is the precursor of lecithin and participates in its synthesis. The main pharmacological effects include protecting the metabolism of choline, ensuring the synthesis of acetylcholine and lecithin in the nerve membrane, and improving blood circulation. To improve cognitive and behavioral responses in patients with brain capillary nerve damage.

HTML of Choline glycerophosphate

 

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COA

 

ltems Standard Results
Appearance White powder,neutral odor,
highly hygroscopic
Conforms
Identification TLC:Standard solution and test
solution same spot,RF
Conforms
Specific Optical -2.4°~-2.8° -2.744°
Heavy metals(as PB) <10ppm Conforms
Sulfate(SO4) ≤0.02% Conforms
Chloride(CI) ≤0.02% Conforms
Phosphate ≤5ppm Conforms
pH 4.5~7.0 5.91
Related substance Spot not bigger than standard
solution spot
No spot
Residual solvent <0.5% Conforms
Water Content <2.0% 0.42%
Assay(dried basis) 98.0%--102.0% 100.52%
Conclusion Conform with enterprise specification

 

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MF of Choline glycerophosphate

Melting point: -98 ° C
Molecular formula: C8H20NO6P
Molecular weight: 257.221
Flash point: 11 °C
Accurate mass: 257.102814
PSA 108.86000
LogP -5.63

 

Is Choline Glycerophosphate the same as choline?

Choline glycerophosphate is a chemical made in the body from choline. It is also made in a lab and used in dietary supplements. Alpha-GPC seems to increase the levels of a chemical in the brain called acetylcholine. This brain chemical is important for memory and learning functions.

 

Does Choline Glycerophosphate increase dopamine?

Clinical trials evaluating the effects of alpha-GPC treatment in patients with Alzheimer's disease indicated an increase in dopamine levels and dopamine active transporter expression in the frontal cortex and cerebellum. This treatment also enhanced serotonin levels in the frontal cortex and striatum of rat brains.

 

Can Choline Glycerophosphate cause insomnia?

Alpha-GPC seems to be safe when used appropriately. It can cause side effects in some people including heartburn, headache, insomnia, dizziness, skin rash, and confusion.

 

The efficacy and function of Choline Glycerophosphate

 

Due to its structural characteristics, Choline glycerophosphate (GPC) contributes to the synthesis of phospholipids in cell membranes, thereby enhancing the fluidity of cell membranes. At the same time, it also has a positive impact on lipid metabolism.

Choline glycerophosphate (GPC) can cross the blood-brain barrier and provide raw materials for the synthesis of the neurotransmitter acetylcholine, thereby increasing the level of acetylcholine in the hippocampus, effectively improving the choline status of the human body, and supporting the functions of the brain and nervous system by increasing the formation of nerve cells and reducing the death of neurons. Enhance the cognitive ability of the brain.

Choline glycerophosphate (GPC) can increase the expression level of genes and prevent the decline in cognitive function caused by aging. This also makes GPC have obvious effects in the treatment of mental disorders such as Alzheimer's disease, amnesia, and cerebral ischemic stroke.

Furthermore, some preliminary evidence suggests that choline glycerophosphate (GPC) can enhance the production.

The increase in growth hormone production and power output can enhance muscle mass and improve overall metabolic activity, thereby improving body composition.

 

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With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.

 

Our Factory

 

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Package

 

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Shipping Methods

 

Transportation Time

Shipping method

Cargo weight requirements

Advantage

3-7 days

DHL,Germany DHL,Germany DPD,
UPS,USPS,FedEx,TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

 

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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
 
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
 
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.

 

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