Atropine sulfate monohydrate powder is a colorless crystalline or white crystalline powder. The melting point is 190-194 ℃. Its 1g crystal can dissolve in 0.4ml of water. This product is a typical M-cholinergic receptor blocker. ① At normal doses, it can relieve gastrointestinal smooth muscle spasms, inhibit glandular secretion, dilate pupils, increase intraocular pressure, cause eye paralysis, increase heart rate, and bronchiectasis At high doses, it can act on vascular smooth muscle, dilate blood vessels, relieve spasmodic contractions, and improve microcirculation. The effect on the smooth muscles of the heart, intestines, and bronchi is stronger and more lasting than other belladonna alkaloids.
| Molecular formula |
|
|
|
Item |
Standard |
Test Results |
|
Appearance |
Off-white or white powder |
white powder |
|
HPLC Identication |
Consistent with the reference substance main peak retention time |
Conforms |
|
Specific Rotation |
+20.0° ~ +22.0° |
+20.9° |
|
Heavy Metals |
≤10ppm |
Conforms |
|
PH |
7.5 ~ 8.5 |
8.2 |
|
Loss on dry |
≤1.0% |
0.04% |
|
Lead |
≤3ppm |
Conforms |
|
Arsenic |
≤1ppm |
Conforms |
|
Cadmium |
≤1ppm |
Conforms |
|
Mercury |
≤0.1ppm |
Conforms |
|
Melting Point |
250.0°C ~ 265.0°C |
253.6°C ~ 254.8°C |
|
Residue on Ignition |
≤0.1% |
0.04% |
|
Hydrazine |
≤2ppm |
Conforms |
|
Bulk density |
- |
0.24g/ml |
|
Tapped density |
- |
0.48g/ml |
|
L-Histidine |
≤0.3% |
0.05% |
|
Assay |
99.0% ~ 101.0% |
99.8% |
|
Total aerobes counts |
≤1000cfu/g |
30cfu/g |
|
Mold & Yeast |
≤100cfu/g |
0.4cfu/g |
|
E.Coli |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
| Conclusion： |
Conform with enterprise specification . |
Can low concentration atropine relieve myopia?
The control effect of Atropine Sulfate Monohydrate Powder on the progression of myopia in children has long received public attention. Based on years of clinical data observation, it has been found that different concentrations of atropine have varying effects on myopia. The higher the concentration, the better the control effect, and 1% atropine can achieve up to 80% control effect. However, clinical studies have found that if the medication is stopped, there will be a certain degree of rebound, and the higher the concentration, the more obvious the rebound effect may be. In addition, white and Asian individuals have different levels of iris pigment and respond differently to atropine. White individuals with less iris pigment are more sensitive to atropine.
What is the mechanism of atropine?
Atropine is an anticholinergic product that antagonizes the M-cholinergic receptor. It is commonly used to rescue septic shock, treat antimony induced Asperger's syndrome, treat organophosphate pesticide poisoning, relieve visceral colic, and for pre anesthesia administration. We found that it can come into contact with smooth muscle spasms (including relieving vascular spasms and improving microvascular circulation); Inhibit glandular secretion; Relieve the inhibition of the vagus nerve on the heart and increase heart rate; Dilating pupils and increasing intraocular pressure, regulating functional paralysis; Excite the respiratory center. According to the conventional pharmacology of this product, researchers initially believed that drugs such as atropine and Tropicamide control myopia through relaxation regulation. However, as research deepened, it was discovered that these products control myopia by directly acting on the retina and sclera.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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