Amitriptyline Hydrochloride Powder CAS 549-18-8
Product Name:Amitriptyline hydrochloride
Synonym:Amiplin;Normaln;Amitriptyline hydrochloride solution;Amitriptyline HCl
CAS NO.:549-18-8
EINECS NO.:208-964-6
Molecular Formula:C20H24ClN
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 5-10 days
Store & Shelf life: Cool & dry place; 24 months
Description
Product description

Amitriptyline hydrochloride powder CAS 549-18-8 is an antidepressant product with both antidepressant and strong sedative effects. It is primarily used for symptoms of endogenous and extrinsic depression, menopausal depression, neurotic depression, and depressive symptoms of organic mental illness. It can also be used for enuresis in children and adolescents.
It improves or eliminates depressive states by blocking the presynaptic membrane of neurons in the brain, preventing the reuptake of 5-HT, increasing the levels of norepinephrine and serotonin at the synapse, and promoting the sensitivity of 5-HT receptors on the postsynaptic membrane. This product has antihistamine and anticholinergic effects, thus producing corresponding beneficial reactions in the body.

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COA
| Tests | Specifications | Results |
| APPEARANCE | COMPLIES | WHITE CRYSTALLINE POWDER |
| IDENTIFICATION | COMPLIES | POSITIVE |
| MELTING POINT | 196.5-197.5℃ | 195-199℃ |
| RESIDUE ON IGNITION | 0.07% | ≤0.1% |
| RELATED SUBSTANCE | COMPLIES | USP32 |
| SINGLE IMPURITY | COMPLIES | USP32 |
| HEVAY METALS | COMPLIES | ≤10ppm |
| LOSS ON DRYING | 0.25% | ≤0.5% |
| PH | 5.7 | 5.0-6.0 |
| ASSAY | 99.32% | 98.0-102.0% |
| Conclusion | Conform with enterprise specification | |
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Density 1.076 g/cm³
Boiling point 398.2°C at 760 mmHg
Melting point 196-197°C
Molecular formula C₂₀H₂₄ClN
Molecular weight 313.864
Flash point 11°C
Exact mass 313.159729 g/cm³
PSA 3.24000
LogP 4.97060 g/cm³
Indications and Applications of Amitriptyline hydrochloride powder CAS 549-18-8
Treatment of various types of depression, with good efficacy for introverted depression, menopausal depression, and reactive depression; It can also be used as an adjunct treatment for obsessive-compulsive disorder, phobias, and neuropathic pain (such as migraines and postherpetic neuralgia).
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Package

Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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FAQ
01. What are the adverse reactions of Amitriptyline hydrochloride powder CAS 549-18-8?
Anticholinergic reactions: dry mouth, constipation, blurred vision, difficulty urinating; these are mostly temporary and gradually become tolerable over time.
Central nervous system reactions: drowsiness, dizziness, tremor; these are more pronounced initially.
Cardiovascular reactions: orthostatic hypotension, tachycardia; elderly patients require extra vigilance.
02. Are there any risks associated with using Amitriptyline hydrochloride powder CAS 549-18-8 in combination with other products?
There are certain interaction risks, and caution should be exercised when using it in combination:
Combined use with monoamine oxidase inhibitors (MAOIs) may trigger a severe hypertensive crisis; such combination is contraindicated.
Combined use with anticholinergics may worsen adverse reactions such as dry mouth and constipation.
Combined use with central nervous system depressants may enhance central nervous system depressant effects and increase the risk of drowsiness.
03. Where can I buy Amitriptyline hydrochloride powder CAS 549-18-8?
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