What is calcifediol vitamin d3?
It is converted from vitamin D3(VD3) in human body under the action of VD3 hydroxylase in liver. It is sensitive to air, heat and light, soluble in polar organic solvents and insoluble in water. Developed and marketed in the 1980s, calcifediol vitamin d3 is used to treat various chronic bone disorders such as osteoporosis in the elderly and metabolic bone diseases related to chronic renal failure.
| Product name |
calcifediol vitamin d3 |
| CAS | 19356-17-3 |
| Molecular formula | C27H44O2 |
| Molecular weight | 400.65 |
| EINECS | 242-990-9 |
| melting point | 74-76oC |
| boiling point | 529.2±33.0 °C(Predicted) |
| density | 1.01±0.1 g/cm3(Predicted) |
| flash(ing) point | 14 °C |
| Storage condition | Store at -20°C |
How does calcifediol vitamin d3 help the treatment of osteopathy?
The natural source of vitamin D in human body mainly depends on the ultraviolet rays of sunlight, which transforms 7-dehydrocholesterol into vitamin D3. At first, vitamin D3 is transformed into calcifediol vitamin d3 under the action of vitamin D3 hydroxylase in the liver. Vitamin D3 mainly exists in the form of calcifediol vitamin d3 in the blood, and calcitriol is further transformed into 1,25-dihydroxy vitamin D3 and 24,25-dihydroxy vitamin D3 in the kidney. The activity of calcitriol is 2-5 times that of it.
calcifediol vitamin d3 can regulate the metabolism of calcium and phosphorus in vivo, promote the absorption of calcium and phosphorus in small intestine, promote the deposition of calcium and phosphorus in bone tissue, and promote the formation of bone. Osteomalacia and rickets (severe osteomalacia causing deformity in children) are characterized by bone mineralization disorder and uncalcified bone-like tissue or cartilage aggregation. Bone changes in vitamin D-related osteomalacia are accompanied by decreased or normal serum calcium and phosphorus levels, increased serum alkaline phosphatase, and secondary increase in PTH. Osteoporosis is characterized by the decrease of bone tissue, which increases the possibility of fracture.
What is the physiological function and function of calcifediol vitamin d3?
Its functions mainly include promoting bone growth, preventing osteoporosis, treating hyperparathyroidism, vitamin D deficiency and rickets.
1. Promote bone growth
Calcifediol Vitamin D3 is an active vitamin D, which can promote the growth of bones, promote the generation of cartilage, and promote the growth and development of the body. Lack of it can lead to delayed growth and development of bones and short stature. At this time, calcitriol capsules and calcium carbonate D3 tablets can be used according to the doctor's advice to promote bone growth.
2. Prevention of osteoporosis
calcifediol vitamin d3 can promote the metabolism of the body, promote the calcification of bones, and prevent osteoporosis to some extent. If the content of calcitriol in the body is low, it may increase the incidence of osteoporosis. At this time, drugs such as alendronate sodium tablets and risedronate sodium tablets can be taken orally according to the doctor's advice.
3. Treat hyperparathyroidism.
It can increase the absorption of calcium in intestine, thus achieving the purpose of treating hyperparathyroidism. If there are diseases such as hyperparathyroidism, there may be symptoms such as bone pain and physical weakness, and patients can use the drug according to the doctor's advice.
4. Treat vitamin D deficiency.
If the vitamin D content in the body is too low, it may lead to the disorder of calcium and phosphorus metabolism in the body, and it is prone to symptoms such as bone pain and muscle spasm. Patients can take calcitriol capsules and calcium carbonate D3 tablets as prescribed, or eat more eggs, milk and other foods for conditioning.
5, treatment of rickets
calcifediol vitamin d3 has a certain effect on rickets, and patients may have symptoms such as restless sleep, easy to wake up, hyperhidrosis, and abnormal bone development. Patients can use drugs such as vitamin D drops and vitamin AD drops under the guidance of doctors, or they can improve by sunbathing.
Product Specification
| Item | Specifications | Result | ||||
|
Appearance |
White to off-white Powder |
Complies |
||||
| Assay (by HPLC) | 97.0% ~ 103.0% | 99.51% | ||||
| Heavy Metals(as Pb) | ≤0.0010% | <0.0010% | ||||
| Total impurities | ≤1.0% | Not detected | ||||
| Individual impurities | ≤0.3% | Not detected | ||||
| Lead | ≤0.5mg/kg | <0.5 mg/kg | ||||
| Arsenic | ≤3mg/kg | <3 mg/kg | ||||
| Mercury | ≤0.1mg/kg | <0.1 mg/kg | ||||
| Cd | ≤0.005mg/kg | <0.005mg/kg | ||||
| Total plate count | ≤1000cfu/g | 30 cfu/g | ||||
| Mould and yeast | ≤100cfu/g | 0 cfu/g | ||||
| E.coli | Negative | Negative | ||||
| Salmonella | Negative | Negative | ||||
| Conclusion: The test results are conformed to the in-house specification | ||||||
How and where to buy calcifediol vitamin d3 wholesale ?
You can trust us completely because we have a good record in selling legal education drugs. Over the years, we have reached Many orders cooperation between Europe and America, which is safe and fast. Have safeguard.
Reasons for choosing us: reliable strength supply, high quality and stable storage, worry-free supply and timely delivery after sale.
Send your Inquiry for more details, Click email：sales7@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email:sales7@faithfulbio.com Now.
Disclaimer: The articles published on this website are mainly used for academic research and technical discussions, which is dialectical and does not mean that this website agrees with all of its views. Please carefully screen. If there is any infringement or other dispute, please contact the administrator. We are not responsible for the consequences of using the information and services on this website.
Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
Hot Tags: Calcifediol Vitamin D3 CAS 19356-17-3, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China