Zinc Pyrithione Powder CAS 13463-41-7

Zinc pyrithione powder has strong killing power against fungi and bacteria, and can effectively kill fungi that produce dandruff, playing a role in dandruff removal. At room temperature, it is a gray white to yellow brown crystalline powder. Slightly distinctive odor. Insoluble in water. It can be made into white non precipitation lotion.

How is the application of ZPT in pearly shampoo?

Zinc pyrithione is stable in the PH range and temperature range required by shampoo, and can be mixed with most shampoo ingredients. However, most manufacturers basically use the traditional method to produce zinc pyrithione, which leads to the large particle size of pure zinc pyrithione. Adding pearlescent shampoo will cover up the pearlescent of shampoo and affect the appearance of shampoo.
The product provided by our company is Zinc pyrithione powder synthesized by special technology, and its particle size is moderate (it is estimated that the particle size is about 2um). Adding it into pearlescent shampoo will not affect the pearlescent effect of shampoo and will not settle.
In addition, according to the relevant research, except for the raw powder of pure zinc pyrithione with special requirements, the pearlescent shampoo will not change when the ZPT suspension is added, and the zinc pyrithione will not settle.

What is the mechanism of action of this product?

The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer ,

In solution, however, the dimers dissociate via scission of one Zn-O bond.A 2011 study showed that the antifungal effect of zinc pyrithione is mediated by the copper toxicity mechanism targeting key iron sulfur proteins. The main method is to disrupt the transport capacity of the membrane by blocking the transport mechanism, and further damage the integrity of the bacterial cell membrane and basic metabolic functions.

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Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Zinc pyrithione powder etc. at a more favorable price. If you are interested, please leave a message.

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