what is Povidone iodine powder?
Povidone iodine powder is an unstable complex formed by the complexation of surfactants with iodine, belonging to the iodophor class of external disinfectants. It is a yellow brown to reddish brown amorphous powder at room temperature. The Povidone iodine powder is a surfactant that helps the solution wet and penetrate objects, thereby enhancing the bactericidal effect of iodine. 80-90% of the bound iodine can be dissociated into free iodine, with high concentration, strong bactericidal power, odorless, non irritating, non allergenic, and low toxicity. As a broad-spectrum fungicide, it can kill viruses, bacteria, spores, fungi, and protozoa. At a concentration of 15ppm, it can kill the reproductive bodies of various bacteria (Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa) within 1 minute. It takes a long time to kill Mycobacterium tuberculosis, 1.5 hours to kill fungi (Bacillus subtilis), and a higher concentration and longer time to kill spores of Bacillus subtilis and Bacillus cereus; Hepatitis B surface antigen (HBsAg) can be destroyed within 10 minutes at 150 ppm concentration. This product can be used not only for skin disinfection, but also for disinfecting metal medical equipment, tableware, etc. At disinfectant concentrations, it is usually red or amber in color and can be directly used on the skin and meninges of surgical patients at the incision site. It can also be used for extracorporeal flushing in obstetrics, gynecology, and urology departments. When its concentration drops below 10ppm, it turns white or pale yellow and loses its bactericidal activity.
 |
Product name |
Povidone iodine |
|
CAS |
25655-41-8 |
|
|
Molecular formula |
C6H9I2NO | |
|
Molecular weight |
364.95 | |
|
EINECS Number |
607-771-8 | |
|
Storage condition |
Keep in dark place,Inert atmosphere,Room temperature | |
|
Appearance |
yellowish-brown powder | |
|
Melting point |
300 °C | |
| Solubility | water:100mg/mL |
what are Properties of Povidone iodine powder?
Povidone iodine powder is a water-soluble iodophor (or iodine-releasing agent) that consists of a complex between iodine and a solubilizing polymer carrier, polyvinylpyrrolidone . In aqueous solution, a dynamic equilibrium occurs between free iodine, the active bactericidal agent, and the PVP-I-complex. After dilution of PVP-I 10% solution, the iodine levels follow a bell-shaped curve and increase with dilution, reaching a maximum at approximately 0.1% strength solution and then decreasing with further dilution There is a good correlation between free iodine concentration and the microbicidal activity of PVP-I
PVP-I (povidone iodine) is a complex of iodine and the solubilizing polymer carrier polyvinylpyrrolidone (PVP) . In aqueous solution, a dynamic equilibrium occurs between free iodine and the PVP-I complex.
What are the indications for Povidone iodine powder?
The main indications for Povidone iodine powder are as follows:
1. Used for purulent dermatitis, fungal skin infections, small area mild burns, and disinfection of small area skin and mucosal wounds.
2. Bacterial and fungal vaginitis, cervical erosion, trichomonas vaginitis, genital itching, genital infection with foul odor and yellowish discharge, comprehensive vaginal inflammation, prevention and local treatment of senile vaginitis, herpes, gonorrhea, syphilis, and genital warts.
3. Disinfection of balanitis, balanitis, external genitalia, and surrounding areas. Prevention and local treatment disinfection of gonorrhea, syphilis, and genital warts.
4. Disinfection of tableware and utensils.
5. Disinfection of the skin at the surgical site.
If you need it, pls click e-mail sales1@faithfulbio.com
Product Specification
|
ITEM |
STANDARD |
RESULT |
|
Appearance |
Reddish brown or yellowish brown powder |
Reddish brown powder |
|
Identification |
A,B |
Confirmed |
|
Loss on drying% |
≤8.0 |
5 |
|
Residue on ignition% |
≤0.025 |
0.015 |
|
Available iodine% |
9.0~ 12.0 |
10.6 |
|
Iodide ion% |
≤6.6 |
4.1 |
|
Nitrogen content% |
9.5~ 11.5 |
9.9 |
|
Heavy metals(as Pb)ppm |
≤20 |
＜20 |
what is the Mechanism of action and antimicrobial spectrum of Povidone iodine powder?
Mechanism of action
As a small molecule, iodine rapidly penetrates into microorganisms and oxidizes key proteins, nucleotides, and fatty acids, eventually leading to cell death . PVP-I has a broad antimicrobial spectrum with activity against Gram-positive and Gram-negative bacteria, including antibiotic-resistant and antiseptic-resistant strains , fungi, and protozoa. It is also active against a wide range of enveloped and nonenveloped viruses , as well as some bacterial spores with increased exposure time. In addition, PVP-I has been shown to have activity against mature bacterial and fungal biofilms in vitro and ex vivo
antimicrobial spectrum
Data are as reported by Lachapelle et al., reproduced under CC-BY license. BC, bactericidal; FC, fungicidal; IS, incomplete spectrum (signifying antimicrobial activity is limited to certain, not all, microbes); LS, large spectrum (signifying a broad spectrum of antimicrobial activity); NA, no activity; PVP-I, povidone iodine; SC, sporicidal; VC, virucidal. Strength: +, weak; ++, medium; and +++, high (based on a subjective analysis of eight papers on antiseptic agents by Lachapelle et al.)
Does Povidone iodine powder cause adverse reactions?
Povidone iodine powder Can cause allergic reactions and irritation to the skin and mucous membranes, but less severe than iodine stimulation. Adverse reactions are rare. However, when applied externally to pregnant women, nursing mothers, and infants, it may cause significant absorption of iodine, local irritation, and burning sensation, which are common reactions. Large scale and long-term use can occasionally cause neutropenia, and severe burn cases can lead to metabolic acidosis, liver damage, as well as contact dermatitis, hypothyroidism, and iodine poisoning
How and where to buy Povidone iodine powder wholesale?
We have 8 years of experience in selling legal scientific research drugs and have a good reputation, making us a trustworthy partner.
We ensure the quality of our products through independent experimental testing, and every customer is our VIP.
Send your Inquiry for more information, Click email：sales1@faithfulbio.comNow.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Disclaimer: The articles on this website are mainly used for scientific research and academic exchange. Please carefully discern the authenticity of their viewpoints and content. If you discover any infringement. Please contact the administrator promptly. We are not responsible for the consequences of the information and services provided on this website.
Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
Send your Inquiry for more details, Click email：sales1@faithfulbio.com Now.
Hot Tags: povidone iodine powder cas 25655-41-8, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China