Muscone API CAS 541-91-3

Muscone API CAS 541-91-3 is a secretion from the sac of male deer, an extremely precious fragrance. As early as the Eastern Han Dynasty, musk was known as the "King of Fragrances." Adding just one ten-thousandth of musk to a fragrance can make it softer, more alluring, and longer-lasting, making it an indispensable fixative in high-end fragrances. Besides its use in fragrances, musk is also recorded as a superior traditional Chinese medicine in medical classics such as the *Shennong Bencao Jing* and Li Shizhen's *Compendium of Materia Medica*, possessing effects such as calming the mind and spirit, clearing the orifices, opening the meridians, and penetrating the muscles and bones, thus having important applications in the medical field.

Musk has a very complex composition, and even now, researchers have not been able to completely isolate and purify its active ingredients. Furthermore, the chemical composition of musk varies significantly depending on the region of origin. Studies have found that the aromatic component of musk is muscone, a macrocyclic ketone compound comprising 2-5% of the total composition, which is also the main active ingredient. It also contains small amounts of other substances. Currently, dozens of androstane derivatives have been isolated from soluble musk ethers, with high-quality musk containing approximately 0.5% androstane derivatives. In addition, musk is rich in fatty acids, cholesterol, esters, and inorganic salts. Another important advancement in the study of musk's chemical composition is the discovery of anti-inflammatory properties in musk water extracts, leading to the isolation of high-molecular-weight peptides with anti-inflammatory effects.