Griseofulvin Powder CAS 126-07-8
Product Name:(+)-Griseofulvin
Synonym:Fulvicin;Lamoryl;Poncyl;Grisovin;Likunden;Spirofulvin;Grizeofulvin
CAS NO.:126-07-8
EINECS NO.:204-767-4
Molecular Formula:C17H17ClO6
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months
Description
Product description

Griseofulvin Powder is a non-polyene antifungal antibiotic that strongly inhibits fungal cell mitosis and interferes with fungal DNA synthesis, and it binds with tubulin to prevent fungal cell division. It has been widely used in the treatment of fungal infection of skin and stratum corneum, and has strong inhibitory effect on trichophyton rubrum, Trichophyton severum and Trichophyton lucidum. Griseofulvins is not only an antibiotic commonly used in the clinical treatment of skin and cuticle fungal infections, but also in agriculture, it is used to control fungal diseases, a candidiasis in apples can cause infection during pollination, and it has a particular effect on this.
Griseofulvin Powder is a colorless crystal, neutral, insoluble in water, and has strong internal absorption. It is stable to environmental factors in vitro and in vivo and between pH3.0 and 8.8 in plants, and can prevent a variety of plant fungal diseases. The main strains of griseofulvins produced in China are penicillium nigricum and penicillium urticum. On the medium, the fur of penicillium nigricum is original fuzz, pure gray when newly cultured, and dark gray when aged, with deep orange-red to orange-brown on the back side. Penicillium urticaria's moss is yellowish-green to pure bright gray, thick and dense, and the back side is cloudy yellow to brown, and their air mycelia are very like broomsticks.

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COA
| Item | Standard | Test Results |
| Appearance | A white microfine powder | Complies |
| Particle size | 95% no more than 5μm | Complies |
| Identification | IR,HNMR and HPLC retention time. | Complies |
| Solubility Test | Practically insoluble in water,freely soluble in dimethylformamide and in tetrachloroethane,slightly soluble in ethanol and methanol. | Complies |
| Appearance of solution | The solution is clear; Not more intensely coloured than reference solution Y4 | Complies |
| Melting point | 220℃ | 219℃~220℃ |
| Specific rotation | Calculated with reference to the dried | +356° |
| substance +354° ~ +364° | ||
| Loss on drying | ≤1.0% | 0.03% |
| Sulphated ash | ≤0.20% | 0.17% |
| Acidity | Not more than 1.0ml of 0.02M | 0.4ml |
| sodium hydroxide is required | ||
| Dechologriseofulvin | ≤0.60% | 0.30% |
| Dehydrogriseofulvin | ≤0.15% | 0.10% |
| Substances soluble in light | ≤0.20% | 0.08% |
| petroleum | ||
| Assay | 97.0%~102.0% | 99.40% |
| (anhydrous substance) | ||
| Abnormal toxicity | Five mice orals,none of the mice dies or abnormal phenomena within 48h | Complies |
| Conclusion | Conform with enterprise specification . | |
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What is griseofulvin used to treat?
Griseofulvin Powder is used to treat skin infections such as jock itch, athlete's foot, and ringworm; and fungal infections of the scalp, fingernails, and toenails. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Is griseofulvin safe?
Griseofulvin has been shown to cause liver and thyroid tumors in some animals. You and your doctor should discuss the benefits of this medicine, as well as the risks of using it.
Is griseofulvin natural?
Griseofulvin was originally isolated in 1939 as a natural product of Penicillium griseofulvum. It interferes with fungal microtubule formation, disrupting the cell's mitotic spindle formation and arresting the metaphase of cell division.
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Transportation Time |
Shipping method |
Cargo weight requirements |
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3-7 days |
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Suitable for under 50kg. |
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By Air |
Suitable for more than 50kg. |
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By Sea |
Suitable for more than 500kg. |
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