What is Erdafitinib powder?
Headquartered in Xi'an, a historic city along the ancient Silk Road, Xi'an Faithful BioTech Co., Ltd. benefits greatly from the region's mature logistics network and rich specialty chemical reserves. Leveraging these local strengths, we have grown into a comprehensive fine chemical supplier serving global overseas purchasers. Our factory, a Chinese manufacturer of cognitive raw materials and pharmaceutical API powders, provides Erdafitinib powder. Erdafitinib (CAS 1346242-81-6) is a small organic molecule for laboratory research. With molecular formula C₂₅H₃₀N₆O₂ and molecular weight 446.54, it exists as pale yellow solid powder at room temperature. This compound binds to FGFR family members including FGFR1, FGFR2, FGFR3 and FGFR4. In vitro tests reveal high binding affinity to these targets, with IC₅₀ values of 1.2 nM, 2.5 nM, 3.0 nM and 5.7 nM. Published studies indicate it is widely adopted in cell-based and in vitro basic research to examine target-related signaling pathway mechanisms.
What are the applicable research scenarios for Erdafitinib powder?
Erdafitinib powder (CAS 1346242-81-6) serves primarily as a chemical raw material for scientific research, specifically for fundamental studies involving the fibroblast growth factor receptor (FGFR) family. It enables enzymatic assays, cell-based model experiments, and investigations into related signaling pathway mechanisms, as well as in vitro studies on molecular binding properties and target structure. It is suitable for use by research institutions and laboratories in project screening, activity assessment, and the exploration of lead compounds.
COA
| Items | Specification | Results |
| Appearance | Yellow solid | Conforms |
| NMR | Conforms to structure | Conforms |
| Infrared Spectrum | Conforms to structure | Conforms |
| Assay | ≥98.5% | 99.4% |
| Conclusion | Conform with enterprise specification | |
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Density 1.20±0.1 g/cm³ (Predicted)
Boiling Point 662.3±55.0 °C (Predicted)
Molecular Formula C25H30N6O2
Molecular Weight 446.54
Flash Point 354.4±31.5 °C
Exact Mass 446.243011
PSA 77.33000
LogP 3.60
InChIKey OLAHOMJCDNXHFI-UHFFFAOYSA-N
What is the mechanism of action of Erdafitinib powder?
1. Erdafitinib powder occupies the ATP-binding pocket within the kinase domain of the FGFR family, inhibiting the functional activity of FGFR1, FGFR2, FGFR3, and FGFR4.
2. Erdafitinib prevents FGFR autophosphorylation, thereby blocking the activation of these receptors.
3. It interrupts downstream signaling cascades such as RAS/MAPK and PI3K/AKT, modulating intracellular signal transduction.
4. It reduces the survival of cell lines harboring FGFR gene alterations, supporting in vitro mechanistic studies using relevant cellular models.
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Shipping Methods
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
FAQ
01. What are the basic molecular details of Erdafitinib powder CAS 1346242-81-6?
This small-molecule compound has the molecular formula C25H30N6O2 and a molecular weight of 446.54; its research code is JNJ-42756493.
02. What are the solubility characteristics of Erdafitinib powder CAS 1346242-81-6?
Erdafitinib powder is readily soluble in DMSO but has low solubility in ethanol and is virtually insoluble in aqueous systems; DMSO is the preferred solvent when preparing experimental solutions.
03. What are the recommendations for transporting Erdafitinib powder CAS 1346242-81-6?
During transport, the product should be sealed and protected from light; low-temperature conditions should be maintained as much as possible, and exposure to high temperatures or prolonged intense light should be avoided to prevent changes in the sample's properties.
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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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