Emtricitabine is a novel nucleoside reverse transcriptase inhibitor. Its chemical structure differs from other nucleoside analogues widely used in clinical practice in that it has a fluorine group at the 5-carbon position, and its mechanism of action is similar to Lamivudine. It has a longer half-life than 3TC plasma and better antiviral activity. Pure FTC is a white or off white crystalline powder with a slight odor. Emtricitabine powder is soluble in water or methanol, slightly soluble in anhydrous ethanol, and insoluble in ethyl acetate or dichloromethane.
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Item |
Requirements |
Test Results |
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Description |
A whiteor almost white crystalline powder |
white crystalline powder |
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Identification |
Conform with spectrum off the reference standard |
Complies |
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Enantiomer |
≤0.50% |
N.D |
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Relatedsubstance |
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5-Flucytosine |
≤0.20% |
0.02% |
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Total impurities |
≤1.0% |
0.30% |
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Residual solvents |
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Ethanol |
≤0.50% |
0.10% |
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Dichloromethane |
≤0.06% |
N.D |
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DMF |
≤0.088% |
ND |
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Ethyl acetate |
≤0.50% |
0.11% |
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Toluene |
≤0.089% |
N.D |
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Residue on ignition |
≤0.20% |
0.10% |
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Specific optical rotation |
-133 ~-143 |
-139.6 |
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Water |
≤0.50% |
0.10% |
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Heavy Metal |
≤20ppm |
Complies |
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Loss on drying |
≤1.0% |
0.20% |
| Assay | 98.0%-102.0% | 99.70% |
| Conclusion | Meets the Requirements |
Comparison between Emtricitabine and other products?
Aids blocking drugs include lamivudine, emtricitabine, tenofovir, abacavir,Raltegravir and Dolutegravir so on. Knowing different products is a prerequisite for cocktail therapy!
1. Lamivudine is suitable for the treatment of chronic hepatitis B.. For AIDS patients, the drug can be combined with other antiretroviral drugs for the treatment of HIV-infected people. Patients with renal insufficiency need to adjust the dose.
2. Emtricitabine can be used for the combined treatment of HIV-1 infected patients in adults and children over 4 years old. This product can selectively inhibit the activity of HIV reverse transcriptase, thus inhibiting HIV replication. It is recommended to take it on an empty stomach to improve bioavailability.
3. Tenofovir plays an antiviral role mainly by phosphorylation into active triphosphate form, which can inhibit the replication of HIV and HBV. Therefore, tenofovir can be used to treat chronic hepatitis B and HIV infection. Patients with renal function injury should use it with caution.
4. Abacavir is suitable for the treatment of HIV infection in combination with other antiretroviral drugs. This product is a nucleoside reverse transcriptase inhibitor, which can specifically inhibit HIV-1 reverse transcriptase and prevent it from synthesizing DNA. Patients with severe immunodeficiency are prohibited.
5. Raltegravir is suitable for combination with other antiretroviral drugs. In the presence of Latiravir, integrase protein can be inactivated, thus achieving the effect of blocking HIV. Patients with mild to moderate renal impairment do not need to adjust the dose.
6. Dolutegravir is an inhibitor of HIV integrase, which can mainly prevent HIV from entering cells to achieve its goal. It can be used in combination with other antiretroviral drugs to treat HIV-1 infection.
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| 134678-17-4 Lamivudine | 143491-57-0 Emtricitabine | 147127-20-6 Tenofovir |
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| 136470-78-5 Abacavir | 518048-05-0 Raltegravir | 1051375-16-6 Dolutegravir |
Dr. He Dayi, a Chinese-American scientist, found in his research that single drug therapy is easy to produce drug resistance. Three or more drugs should be used in combination to improve the therapeutic effect and inhibit the replication of the virus to the maximum extent, which is the same as the process of preparing cocktails. Although "cocktail" therapy can not completely cure AIDS, it is the most effective way to block the attack of AIDS at present. Our company, in cooperation with many companies, can provide more product ingredients for your formula research process, including the products I just listed, such as lamivudine and emtricitabine, as well as raw materials for products that have not been mentioned, such as efavirenz. If you are interested, Please contact me a message by email:sales6@faithfulbio.com
Can emtricitabine prevent HIV?
AIDS is mainly an infectious disease caused by human immunodeficiency virus. In theory, all drugs that can treat AIDS can prevent AIDS. However, there are legal and social problems for non AIDS people to take medicine, so our country is still under discussion.
AIDS prevention can be divided into two types, namely pre exposure prevention and post exposure prevention. Post exposure prevention is widely implemented in China. If there is high-risk behavior, it is best to go to the hospital within two hours or one day (no longer than 72 hours, and use blocking drugs before arriving at the hospital, and stay away from high-risk factors) to carry out post exposure prophylaxis blocking treatment. The doctor will issue a complete anti-virus treatment program, and the theory also proves that the anti-virus treatment program can effectively prevent AIDS virus infection, and it is very likely that AIDS virus will not be infected. This method was first used for medical personnel who were exposed to occupational hazards, thus avoiding infection among medical personnel.
There are also many drugs to prevent AIDS, such as zidovudine, lamivudine, tenofovir, Dolutegravir, and integrase inhibitors, which can be used for the prevention of AIDS virus after exposure. However, it should be noted that some products alone can not block AIDS. For example, pure emtricitabine powder needs to be combined with other antiviral drugs to effectively block AIDS.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Can provide you with a good price.If you are interested in Emtricitabine, Lamivudine and other raw materials, please let us know.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.
If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email ：sales6@faithfulbio.com . Our team is committed to ensuring the complete satisfaction of customers.
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