What is CMS-121?
CMS121 Powder is a quinolone derivative and an orally active acetyl CoA carboxylase 1 (ACC1) inhibitor. It protects HT22 cells from ischemia and oxidative damage with EC50 values of 7nM and 200nM, respectively. It has strong neuroprotective, anti-inflammatory, antioxidant, and renal protective effects.
Xi'an Faithful BioTech Co.,Ltd focuses on the research and development, production and sales of chemical raw materials.Our enduring commitment is "Providing customers worldwide with the highest quality chemical raw materials and the most professional procurement services "!
| Product name | CMS121 Powder |
| CAS | 1353224-53-9 |
| Molecular formula | C20H19NO3 |
| Molecular weight | 321.37 |
| EINECS Number | NA |
| melting point | NA |
| solubility | NA |
| Storage conditions | Store at -20°C |
| Appearance | pale yellow powder |
| boiling point | 511.0±50.0 °C |
| Density | 1.297±0.06 g/cm3 |
Product Specification
| Item | Specification | Results |
| Purity(On Dried Base,%) | >99% | 99.38% |
| Appearance | pale yellow powder | Complies |
| Loss on Drying | ≤1.0% | 0.42% |
| Residue on ignition | ≤0.5% | 0.25% |
| Heavy metals (As Pb) | NMT20PPM | Conforms |
| Related substance | Max Single Impurity≤0.5% | 0.12% |
| Conclusion | Conform with enterprise specification | |
Where is CMS-121 used?
CMS121 Powder is commonly used in research on neuroprotection, anti-inflammatory, antioxidant, and renal protection,
Neuroprotection: It protects HT22 cells from ischemia and oxidative damage and has a strong neuroprotective effect.
Anti inflammatory and antioxidant: It can increase acetyl CoA in cells, which can have anti-inflammatory and oxidative effects.
Renal protection: It has a renal protective effect.
In summary, it demonstrates potential therapeutic value in various biological processes. It should be noted that these research results are mainly based on in vitro and animal experiments, and their application in humans requires further research and verification.
What are the effects of CMS-121 ?
CMS121 Powder has various biological activities and pharmacological effects, with specific effects as follows:
Improving cognitive function: In a mouse model of Alzheimer's disease, its treatment can significantly improve learning and memory problems, making the performance of diseased mice comparable to that of healthy control mice.
Regulating metabolism and delaying aging: It maintains mitochondrial homeostasis, slows down cognitive decline, and reduces aging related metabolic and transcriptional markers in the brain by regulating acetyl CoA metabolism.
Inhibition of fatty acid synthase: It reduces the level of FASN, which in turn lowers lipid peroxidation levels, indicating that FASN may be a drug target for treating Alzheimer's disease.
In summary, it exhibits significant biological activity in neuroprotection, anti-inflammatory, antioxidant, renal protection, improving cognitive function, regulating metabolism, and delaying aging.
How and where to buy CMS121 Powder wholesale?
Our products undergo experimental testing and are recognized by customers.
You can trust our order because we have a good record of selling legal educational drugs.
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
Please contact me, I am Tina, a sales from Faithful. I will provide you with professional service to ensure your shopping experience is enjoyable and secure.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
FAQ：
Q1:Can you use customer-specific labeling and packing?
A1:Of course, you can provide us with the specified labeling and packaging and we will be happy to follow up with you.assist you. If there is anything else you need, please feel free to communicate with us!
Q2:What are your advantages?
A2:we have more than 10 years of experience and have never given up even if it is not so easy, which is not very common among our peers. Therefore, we have a long-term and very stable relationship with many manufacturers in China, which can provide you with a high-quality and solid supply chain.
Q3: How about delivery time and method?
A3:We usually ship within 1-3 working days after payments.We can make ships by sea, air, or express. Also can make door-to-door shipping.
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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