Cilostazol CAS 73963-72-1

Cilostazol is white or white-like crystalline powder, odorless. The melting point is 157 ~ 161℃, and the maximum UV absorption (methanol) is 257nm(ε15200). Pure cilostazol is soluble in glacial acetic acid, dimethyl sulfoxide or chloroform, soluble in N,N- dimethylformamide, slightly soluble in methanol or anhydrous ethanol, and almost insoluble in water, 0.1mol/L hydrochloric acid solution or 0.1mol/L sodium hydroxide solution.

What is the difference between cilostazol and aspirin?

There are significant differences between cilostazol and aspirin in terms of their main components, chemical structure, mechanism of action, therapeutic effects, side effects, and medication precautions. If there are any discomfort symptoms, timely medical attention should be sought.
1. Main components and chemical structure: The main component of cilostazol is cilostazol, which belongs to the quinoline derivatives. The main component of aspirin is acetylsalicylic acid, which belongs to the salicylic acid class of drugs.

2. Mechanism of action: Cilostazol exerts antiplatelet and vasodilatory effects by inhibiting the activity of phosphodiesterase in vascular smooth muscle and platelets, increasing the concentration of cAMP (cyclic adenosine monophosphate) in vascular smooth muscle and platelets. Aspirin mainly works by inhibiting platelet aggregation. It inhibits platelet release reactions, prevents platelet aggregation, and makes it difficult to release clotting factors, thus having a certain anticoagulant effect.

3. Indications: Cilostazol is mainly used to improve ischemic symptoms caused by chronic arterial occlusion, such as limb pain, ulcers, etc., and prevent the recurrence of cerebral infarction. Aspirin tablets are suitable for inhibiting platelet aggregation and reducing the incidence of myocardial infarction, temporary cerebral ischemia or stroke in patients with atherosclerosis etc. It can also be used for antipyretic, analgesic, and anti-inflammatory treatment.

4. Side effects: Common side effects of cilostazol include headache, palpitations, diarrhea, fatigue, dizziness, hypotension, and bradycardia. Some patients may experience liver dysfunction and respiratory symptoms. The side effects of aspirin mainly include gastrointestinal discomfort (such as nausea, vomiting, abdominal pain), bleeding (such as gum bleeding, skin bleeding points, etc.), and allergic reactions. Long term high-dose use may lead to gastric ulcers and bleeding.

5. Medication precautions: When taking cilostazol, attention should be paid to its potential to cause liver function damage, so liver function should be monitored regularly. In addition, pregnant and lactating women should use caution. When taking aspirin, attention should be paid to its potential increase in bleeding risk, especially for patients with a tendency to bleed. In addition, aspirin may increase the risk of bleeding when used in combination with certain medications such as warfarin, and should be used with caution.

Our company can provide you with Acetylsalicylic acid, Cilostazol,Warfarin and Clopidogrel at a better price. If you are interested, please contact us by email:sales6@faithfulbio.com

What are the differences of cilostazol tablets in antiplatelet therapy?

After using cilostazol, it can inhibit platelet aggregation caused by thromboxane A2 by inhibiting the phosphodiesterase activity of platelets, so this product is an anti-platelet aggregation drug, but the mechanism of pure cilostazol may be different from aspirin, clopidogrel and other commonly used anti-platelet drugs. It can not only resist platelet aggregation, but also improve the blood flow at the end of artery, dilate blood vessels and improve the symptoms of lower limb pain, cold feeling and intermittent claudication caused by arterial occlusion. Simply put, it can not only prevent platelets from accumulating into a group, so as not to form thrombus, but also relax blood vessels and make blood flow smoother.(relatively speaking, aspirin is more like a pioneer in emergency treatment, which can be used to treat sudden cerebrovascular diseases. However, if this product is used for a long time to prevent thrombosis, stents may be needed to deal with the problem of vascular blockage.)Therefore, this product should be used differently. Cilostazol should not be used in patients with severe hemorrhagic heart failure, patients with abnormal liver function, patients with continuously rising blood pressure and patients in unstable period after cerebral infarction. However, the safety of this product is higher than that of aspirin and clopidogrel. If the patient's condition permits, patients who are intolerant of aspirin and other drugs, or patients who want to improve ischemic symptoms such as ulcer, limb pain, cold sensation and intermittent claudication caused by chronic arterial occlusion, and to prevent more serious ischemic stroke, can give priority to this product.
Another study shows that cilostazol is similar to aspirin in preventing cerebral infarction, but cerebral hemorrhage is significantly lower than aspirin.

A variety of shipping methods for you to choose

Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can offer Aspirin,Cilostazol,Warfarin and Clopidogrel at a low price. If you need it, please leave a message

We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.

If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email ：sales6@faithfulbio.com   . Our team is committed to ensuring the complete satisfaction of customers.

Hot Tags: cilostazol cas 73963-72-1, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China