Carprofen Powder CAS 53716-49-7

Carprofen powder is a white crystal with molecular formula of C15H12C1N02, molecular weight of 273. 72 and melting point of 207208 C. It is insoluble in water and soluble in organic solvents such as acetic acid. Its main chemical composition is 2-(6-Chloro-9H-carbazol-2-yl)propanoic acid.

What is the difference between Carprofen, Ibuprofen, Ketoprofen, and Loxoprofen Sodium?

These four products belong to analgesic products, but there will be some differences in the treatment direction. Pure Carprofen is a non-steroidal anti-inflammatory drug, which can block the transformation of arachidonic acid into prostaglandin by inhibiting the activity of cyclooxygenase, thus playing an antipyretic, analgesic and anti-inflammatory role. Clinically, it is mainly used to relieve mild to moderate pain and treat inflammation, such as headache and joint pain. It can also be used to relieve symptoms such as fever and runny nose caused by cold. The mechanism of action of Ibuprofen is very similar to that of Carprofen, which is achieved by reducing the synthesis of prostaglandin. However, in application, it is more powerful. It can not only reduce the pain signal transmission by inhibiting the release of inflammatory mediators and the activation of neurons, so as to alleviate the pain feeling. It can also reduce the synthesis of prostaglandin in hypothalamus by affecting the thermoregulatory center of hypothalamus, thus reducing body temperature. At present, the most commonly used products in clinic are mainly used to treat mild and moderate pain, such as headache, toothache, migraine, nerve pain and menstrual pain. Pure Ibuprofen can also be used to treat fever caused by cold, but it is not as good as Ketoprofen in analgesia.Pure Ketoprofen is mainly used for joint pain caused by rheumatism and rheumatoid arthritis and muscle swelling pain caused by various reasons. The most effective one is Loxoprofen sodium, and it has no obvious irritation to gastrointestinal tract. It is often used to treat osteoarthritis, lumbago and leg pain, scapulohumeral periarthritis, toothache and rheumatoid arthritis. It can also be used to treat pain caused by surgery, trauma and upper respiratory tract infection.

Our company can not only rely on Carprofen, Ibuprofen, Ketoprofen, And Loxoprofen Sodium, We can also customize other similar pharmaceutical ingredients for you to use. If you have any needs, please contact us via email:sales6@faithfulbio.com.

Has the market for Carprofen products completely given way to new analgesic products?

Carprofen powder, as a once popular anti-inflammatory and analgesic product, was successfully developed by Roche Company in 1980s. Because of its small side effects, the analgesic and anti-inflammatory effect is obviously better than traditional anti-inflammatory and analgesic products such as Diclofenac sodium and Phenylbutazone. This makes it widely approved and applied in the United States, Canada and many European countries. After serving human medicine for 10 years, it gradually withdrew from the market around 1995 for some commercial reasons. However, it still occupies a large market in the veterinary drug market, especially in alleviating the pain of animals in old age. It is well tolerated, and most adverse reactions are mild, such as gastrointestinal pain and nausea, similar to those recorded by aspirin and other non-steroidal anti-inflammatory products.

Improper use of Carprofen will hurt your dog.

one:What are the usual reasons for the toxicity of Carprofen to dogs?

1. Excessive use of this product

2. Pets are extremely sensitive to the side effects of this product.

two:What may be the signs of Carprofen poisoning in dogs?

1. Gastrointestinal symptoms include nausea, loss of appetite, vomiting, diarrhea, black stool (black tarry stool), abdominal pain, and gastric ulcers.

2. Kidney damage can cause symptoms of acute kidney failure in dogs, such as thirst, increased urination, vomiting, diarrhea, loss of appetite, drowsiness, and light urine (lighter color).

3. Symptoms of liver damage include jaundice of the skin, gums, ears, sclera (white eyes), as well as vomiting, diarrhea, loss of appetite, and drowsiness.

three:How to diagnose whether it is Carprofen poisoning?

1. Complete blood count (CBC) is a blood test used to check the white blood cell and red blood cell counts of pets. Carprofen toxicity may cause a slight increase in white blood cell count. Red blood cell count may decrease due to bleeding caused by gastrointestinal ulcers.

2. Biochemical analysis is also a blood test mainly used to measure liver enzyme levels. If the liver is damaged, enzyme levels will increase. In addition, the test also measures kidney function, such as creatinine and blood urea nitrogen (BUN), which are elevated in acute kidney failure. Your veterinarian may repeat this test during pet treatment to ensure that the value is decreasing, indicating that the pet is recovering from toxicity.

3. Urinalysis is used to evaluate the ability of the kidneys to concentrate urine. Animals with acute kidney failure typically exhibit watery urine, as the kidneys are unable to concentrate urine. Urine should also be checked for small pieces of substance. If there are, it indicates that the area called tubules in the kidneys has been damaged. The small tube injury is consistent with the symptoms of Carprofen poisoning.

4. Urine culture and sensitivity analysis to exclude bacterial infections in urine.

5. Evaluate the condition of the kidneys and liver through abdominal ultrasound. It may be necessary to perform ultrasound-guided biopsies of the liver or kidneys to determine the extent of damage to these organs or to confirm whether Carlofen is a potential cause of injury.

four:How to treat and care for pet diagnosed with Carprofen poisoning?
1.If accidentally ingested, please remove any remaining pills around your pet and take your dog to a veterinarian for treatment as soon as possible.
2. If you have already given your dog Carprofen and you notice vomiting, black stools, pale gums, or decreased appetite, stop giving your dog Carprofen and take your dog to a veterinarian as soon as possible.
To prevent toxicity, never exceed the dosage prescribed by your veterinarian. You can mix medicine with food for dogs to take, which also helps prevent stomach discomfort.

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Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,We can not only support the demand for Carprofen, Ibuprofen, Ketoprofen, and Loxoprofen Sodium, but also provide you with Diclofenac Sodium and Phenylbutazone products. If you are interested, please leave a message

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