What is IGF-1R Modulator 1?
ACD856 is a small molecule compound with the CAS number 2375424-89-6 and the molecular formula C22H17N3O4, with a molecular weight of 387.39. As a positive allosteric modulator of Trk receptors, the core mechanism of action of ACD856 powder is to regulate various signaling pathways mediated by nerve growth factor and brain-derived neurotrophic factor.
In practical applications, IGF-1R modulator 1 is mainly used as a research tool compound and is mostly employed to study the related diseases caused by abnormal signaling of neurotrophic factors. This substance can effectively enhance the signal transmission between neurons and has the potential to improve cognitive functions. IGF-1R modulator 1 was independently developed by the Swedish biotech company AlzeCure Pharma and is a core candidate compound of its NeuroRestore technology platform. Currently, IGF-1R modulator 1 has completed the Phase I clinical trial in healthy subjects, and the experimental data confirm that it has excellent oral bioavailability and good human tolerance.
What are the differences between IGF-1R modulator 1 and common brain-boosting health supplements?
Conventional brain-boosting ingredients usually exert their effects indirectly by improving blood flow in the brain, providing nutritional support, or antioxidation, and their effects are relatively broad. However, ACD856 powder has a more targeted effect. It does not "supplement nutrients" to the brain, but specifically regulates the signaling pathways related to neurotrophic factors (such as NGF and BDNF) in a precise manner. In simple terms, IGF-1R modulator 1 is like "turning up" the switch for signal transmission between neurons, allowing the existing nutritional signals to be utilized more efficiently, rather than adding new external signals.
What are the main exploration directions of IGF-1R modulator 1?
The current research focus is not on repairing damaged neurons, but rather on how to maintain and optimize the efficiency of neural signal transmission in a healthy state. The research mainly focuses on cognitive function changes related to aging, such as the ability to learn new things and the retention of short-term memory. At the non-clinical level, ACD856 powder is more often used as a tool to understand the process of neural signal communication. By observing its performance in cell models or related systems, it helps researchers clarify the relationship between the functions of neurotrophic factors and cognitive performance, and accumulate basic data for further application development.
MF of IGF-1R modulator 1
| CAS | 2375424-89-6 |
| Molecular formula | C22H17N3O4 |
| Density | 1.338±0.06 g/cm3 |
| Molecular weight | 387.39 |
Specification
| Item | Specification | Result |
| Appearance | White powder | Complies |
| Assay | ≥98.0% | 98.23% |
| Conclusion | Conform with enterprise specification | |
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| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
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FAQ:
Q1:Does eating have any effect on the absorption of ACD856?
A high-fat diet will reduce its concentration and delay the time to reach the peak effect, but it has little impact on the overall bioavailability and half-life.
Q2:What is the relationship between ACD856 and the previous generation candidate ACD855?
ACD855 was abandoned due to its excessively long half-life in the human body. ACD856 was an improvement based on this. Preclinical evaluations confirmed that its half-life was more suitable for further development.
Q3:To what extent does ACD856 enter the brain?
Clinical data shows that ACD856 can enter the brain at relevant concentrations and activate neural pathways related to cognitive functions and emotions. This is a crucial indicator for research on the central nervous system.
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