Diindolylmethane DIM Raw Powder CAS 1968-05-4

What is Diindolylmethane?

Diindolylmethane DIM raw Powder (3,3'-Diindolylmethane) is a white to off-white crystalline powder, soluble in methanol, ethyl acetate, dichloromethane, and other organic solvents. 3,3'-Diindolylmethane widely exists in the natural plants of the cruciferous family. It has important biological and pharmacological activities and is widely used in the fields of medicine and health care products.

Diindolylmethane Benefits

Diindolylmethane DIM raw Powder is mainly used in:

DIM is a potent radioprotector and reliever, acting by stimulating ATM-driven DDR-like responses and NF-κB survival signaling. DIM can inhibit tumor cell invasion, angiogenesis, and proliferation and induce apoptosis by regulating signaling pathways such as AKT, NF-κB, and FOXO3. It also inhibits estrogen-induced gene expression and induces endoplasmic reticulum stress. DIM can alter estrogen metabolism and antagonize estrogen and androgen receptor activity. After multiple doses of DIM, it is effective against systemic radiation. In in vivo tests, DIM has radioprotective or mitigating effects. In normal tissue, DIM activates ATM. DIM can be administered to mice by oral gavage (250mg/kg), with high bioavailability and no acute toxicity

Application of Diindolylmethane

Pharmaceutical intermediate; can be found in natural phytochemicals belonging to cruciferous plants, acid-catalyzed reaction product, indole-3-carbinol; has the function of an anti-tumor agent; this derivative, under relatively high concentration conditions, both can directly accelerate the apoptosis of human cancer cells, and can also sensitize TRAIL to induce the apoptosis of human cancer cells; DIM induces a G1 cell cycle inhibition, in human breast cancer MCF-7 cells, through the mechanism, including expression; DIM is a strong Potent inhibitor of mitochondrial H+-ATPase; as new plant growth promoters, the functions of DIM and its derivatives have been used in eco-friendly system studies

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How To Obtain Samples of Diindolylmethane?

Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API powder Diindolylmethane.

The Best Diindolylmethane Manufacturer And Supplier

Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.

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Why Choose Faithfulbio Diindolylmethane?

Faithfulbio specialize in Diindolylmethane for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.

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kindly note: Use this compound for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.

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