Oxcarbazepine powder is a prodrug. It is a structural analog of the 10- keto group of carbamazepine, and most of it is metabolized into active 10- hydroxy metabolites in vivo.
Oxcarbazepine powder is a 10- keto derivative of carbamazepine, and its efficacy is similar to or slightly stronger than that of carbamazepine. Carbamazepine and its metabolites (hydroxyl derivatives) have anticonvulsant activity and highly selective inhibition of cerebral cortex movement, which may be due to blocking the voltage-dependent sodium channel of brain cells, thus preventing the spread of focal discharge. In addition, oxcarbazepine also acts on potassium and calcium channels.
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| Real shot pictures of Oxcarbazepine | Oxcarbazepine structure diagram |
Product Application
1. Oxcarbazepine powder can block voltage-dependent sodium channels in brain cells,
2. It can stabilize the overactive nerve cell membrane,
3. It can inhibit the repetitive discharge of neurons,
4. It can reduce the excitatory impulses transmitted through synapses.
Product Specification
Item | Specification | Results |
Appearance | A white or almost white, crystalline powder | Conforms |
Identification | IR & UV & HPLC | Conforms |
Solubility | Soluble in methanol and ethanol, insoluble in water | Conforms |
Melting point | 222 ~ 228 ℃ | 223 ~ 224 ℃ |
Loss on drying | ≤0.3% | 0.21% |
Residue on Ignition | ≤0.2% | 0.09% |
Relative substance | Carbamazepine ≤0.2% | 0.14% |
Unknow impurities ≤0.5% | <0.5% | |
Total impurities ≤1.0% | 0.54% | |
Assay | ≥99.0% | 99.56% |
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure or prevent any disease.
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