Metoclopramide API Powder CAS 364-62-5
Product Name:Metoclopramide API powder
CAS NO.:364-62-5
Molecular Formula:C14H22ClN3O2
EINECS.NO:206-662-9
Synonym:Metoclopramide;4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide;Methoxychloroprocainamide
Shipping:DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life:Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany
Description
what is Metoclopramide API powder?
Metoclopramide API powder is an antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. It is a kind of white powder.
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Product name |
Metoclopramide |
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CAS |
364-62-5 |
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Molecular formula |
C14H22ClN3O2 | |
| EINECS | 206-662-9 | |
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Molecular weight |
299.8 | |
| Melting point | 146-148°C | |
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Appearance |
white powder |
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| Density | 1.2432 (rough estimate) |
What are the main uses of Metoclopramide API powder?
As an active pharmaceutical ingredient, Metoclopramide API powder can be used to prepare formulations such as injections, tablets, or oral liquids, and related formulations can be:
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As a gastric motility drug, metoclopramide can enhance gastrointestinal peristalsis, accelerate gastric emptying, and improve symptoms such as dyspepsia, gastroesophageal reflux (GERD), and gastroparesis (such as delayed gastric emptying caused by diabetes).
It has antiemetic effects and is commonly used to treat nausea and vomiting caused by chemotherapy, radiotherapy, surgery, or pregnancy, especially for central and gastrointestinal vomiting.
Used before gastroscopy or radiographic imaging, it can reduce gastric residues and improve examination clarity. |
In addition to the above points, in the veterinary field, Metoclopramide may be used for the treatment of animal digestive system diseases.If you need it, pls click e-mail: sales1@faithfulbio.com
Product Specification
| Items | Specification | Results |
| Appearance | White to off-white powder | Complies |
| Identification | Both NMR and MS data are consistent with those reported in the literature | Complies |
| Water content | ≤6% | 4.8% |
| Residue on ignition | ≤0.1% | 0.05% |
| Total impurities | ≤0.5% | 0.06% |
| Any single impurity | ≤0.1% | 0.04% |
| Heavy metals | ≤20ppm | Complies |
| Assay (on the anhydrous basis) | ≥98.5% | 99.5% |
| Conclusion：Conform with enterprise specification | ||
how Metoclopramide API powder works?
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Metoclopramide causes antiemetic effects by inhibiting dopamine D2 and serotonin 5-HT3 receptors in the chemoreceptor trigger zone (CTZ) located in the area postrema of the brain. Administration of it leads to prokinetic effects via inhibitory actions on presynaptic and postsynaptic D2 receptors, agonism of serotonin 5-HT4 receptors, and antagonism of muscarinic receptor inhibition. This action enhances the release of acetylcholine, causing increased lower esophageal sphincter (LES) and gastric tone, accelerating gastric emptying and transit through the gut. Metoclopramide API powder antagonizes the dopamine D2 receptors. Dopamine exerts relaxant effect on the gastrointestinal tract through binding to muscular D2 receptors. |
How and where to Buy Metoclopramide API powder?
We have 8 years of experience in selling legal scientific research drugs and have a good reputation, making us a trustworthy partner.
We ensure the quality of our products through independent experimental testing, and every customer is our VIP.
Send your Inquiry for more information, Click email：sales1@faithfulbio.comNow.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
FAQ
Q: What type of antiemetic is metoclopramide?
A:Metoclopramide is an antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
Q:Are Ondansetron and metoclopramide products in the same category?
A:Ondansetron and metoclopramide belong to different drug classes. Ondansetron is an anti-nausea product and metoclopramide is a "prokinetic" product.
Q: What express delivery do you use for transportation?
A:Our final journey usually chooses one of UPS/Fedex/DHL or POSTQ based on the recent transportation situation.
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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
Send your Inquiry for more details, Click email：sales1@faithfulbio.com Now.
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