S-Acetyl-L-Glutathione Powder Raw Material CAS 3054-47-5

S-Acetyl-L-glutathione Introduction

S-Acetyl-L-Glutathione powder raw material: CAS  3054-47-5. It is obtained by structurally modifying Glutathione. The molecular formula is C12H19N3O7S. The introduction of N-Acetyl-L-Tyrosine ethyl ester makes the molecule less likely to be rapidly decomposed and destroyed in the digestive tract, and the duration of its effect is also longer. When it reaches the target site, this layer of N-Acetyl-L-Tyrosine ethyl ester will gradually fall off, releasing the active Glutathione to work. Based on this characteristic, S-Acetyl-L-glutathione is often used in dietary nutrition supplement products to help maintain the body's glutathione reserves. In the food industry, S-Acetyl-L-glutathione can be used as an antioxidant component to delay oil oxidation and inhibit the deterioration of product color. In the research field, Glutathione-S-acetate is also used as an experimental reagent and is used to study the mechanisms related to acetyl transfer and energy transfer.

What is the difference between S-Acetyl-L-glutathione and Glutathione?

Glutathione contains free sulfhydryl groups, which are easily oxidized. They are rapidly decomposed by enzymes in the digestive tract, and many components lose their activity before being absorbed. S-Acetyl-L-glutathione is a modified precursor. An acetyl group is attached to the sulfhydryl site as a protective structure. It can remain stable during the transport process in the digestive tract and the acetyl group will only be removed after absorption, releasing the active Glutathione.
From an application perspective, ordinary Glutathione has poor stability in liquid formulations and limited oral absorption levels. S-Acetyl-L-Glutathione powder raw material has high absorption efficiency and stronger stability, and is mostly used in dietary supplements. Both can exert antioxidant effects, but S-Acetyl-L-glutathione is mainly used to improve the insufficient stability of natural Glutathione.

The uses of S-Acetyl-L-glutathione

The application value of S-Acetyl-L-glutathione goes far beyond basic antioxidant functions. Numerous studies in various fields have verified its multi-functional properties. In terms of liver maintenance, animal experiments have shown that this component can effectively restore the Glutathione and superoxide dismutase activities in damaged organisms, inhibit lipid peroxidation reactions and the release of inflammatory factors, and assist in improving liver fibrosis problems; in clinical cases of pet spontaneous liver diseases, supplementing this raw material can increase the content of glutathione in red blood cells and steadily optimize various liver function indicators.
In antiviral research, for herpes simplex 1 infection, Glutathione-S-acetate can repair the intracellular glutathione consumed by the virus at different doses, and its effect is better than that of ordinary Glutathione; animal experiments have also proved that it can reduce the mortality rate of viral infection and effectively reduce the viral load in the organs of infected organisms.
In terms of immune regulation, the S-Acetyl-L-Glutathione powder raw material can avoid the problem of blocked glutathione synthesis during infection of the organism, indirectly helping T cell proliferation and maintaining the normal immune regulatory function of the organism. In addition, this component is also applicable to the field of skin care. Clinical tests have shown that the topical preparations containing this component can improve skin wrinkles, dullness, insufficient elasticity and dryness problems. At a 2% concentration, it can soothe skin redness induced by ultraviolet rays, and at the same time, by inhibiting tyrosinase and eliminating free radicals that cause darkening, it achieves the effect of brightening and skin smoothing.

MF of S-Acetyl-L-glutathione

CAS	3054-47-5
Molecular formula	C12H19N3O7S
EINECS	2212755
Molecular weight	349.36016
Boiling point	770.2±60.0 °C
Density	1.436±0.06 g/cm3

Specification

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FAQ: 

Q1:Can S-Acetyl-L-glutathione be used externally for skin care?

OK. Clinical tests of the topical cream have shown that it can improve fine lines, skin elasticity, moisture content and uneven skin tone.

Q2:What should a formulation engineer pay attention to when using it?

Try to avoid high-temperature processing. Extreme pH conditions will affect the acetyl protection structure. It is recommended to conduct a formulation stability test in advance.

Q3:What skin care benefits can be achieved with a 2% concentration?

Reduce skin redness caused by ultraviolet rays; at the same time, inhibit tyrosinase and eliminate free radicals that promote melanin production, achieving a brightening effect.

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