What is Hexamidine diisethionate?
Hexamidine Diisethionate (hydroxyethyl sulfonic acid) salt is a water-soluble cationic substance, which has broad-spectrum antibacterial and bacteriostatic properties. It has high bactericidal and bacteriostatic properties for various Gram-positive bacteria and negative bacteria, as well as various molds and yeasts, and it is very mild.
In the fields of cosmetics and industrial products, hexamidine bis (hydroxyethyl sulfonic acid) salt is widely used as antibacterial agent and preservative. The recommended dosage is 0.1% of antibacterial agent and 0.01-0.1% of preservative.
Generally speaking, Hexamidine Diisethionate (hydroxyethyl sulfonic acid) salt is an efficient, mild and broad-spectrum antibacterial and bactericide, which is suitable for a variety of personal care products and industrial applications.
| Product name | Hexamidine diisethionate |
| CAS | 659-40-5 |
| Molecular formula | C22H32N4O6S |
| Molecular weight | 480.58 |
| EINECS Number | 211-533-5 |
| Melting point | 246-247° (dec) |
| Solubility | Slightly soluble in water, slightly soluble in ethanol (96%) and almost insoluble in dichloromethane. |
| Appearance | White to light gray |
| Storage condition | 2-8°C |
| Density | 671[at 20℃] |
Product Specification
How does Hexamidine diisethionate dissolve?
Some suggestions on manufacturing Hexamidine diisethionate：
1. Choose the right solvent: Choose the right solvent according to the specific application requirements, such as water, propylene glycol and anhydrous ethanol, which will affect the dissolution effect and the quality of the final product.
2. Temperature control: strictly control the temperature during the dissolution process to ensure that hexamidine can be fully dissolved, and avoid insolubles or insufficient reaction caused by too high or too low temperature.
3. Full stirring: During the dissolution process, ensure full stirring, so that hexamidine can be evenly dispersed in the solvent and the dissolution efficiency can be improved.
The process of dissolving Hexamidine diisethionate：hexamidine dihydroethyl sulfonate can be effectively dissolved, and the dissolution conditions can be adjusted according to the specific application scenarios to obtain the best use effect.
What is the use of Hexamidine Diisethionate?
2. Synthesis steps:
1) synthesizing 4- amidine phenol: 4- cyanophenol was dissolved in absolute ethanol and cooled to room temperature. Dropwise adding 1,6- dibromohexane, keeping the reaction temperature at 30°C, and refluxing for 3 hours. After the reaction, it was cooled to 10°C, stirred for 2 hours, filtered and dried to obtain 4- amidinophenol.
2) synthesizing hexamidine: Dissolve 4- amidinophenol in absolute ethanol and cool to 10°C,and keeping the reaction temperature at 5-10 C until the reactant system increases to a constant weight. keeping the temperature at 25-30 C, and continuously reacting for 72 hours. After the reaction, it was cooled to 10°C, stirred overnight, filtered, and the filter cake was and dried to obtain hexamidine.
3) synthesizing hexamidine dihydroxyethyl sulfonate: Adding hexamidine into anhydrous ethanol, and stirring at low temperature for 20-30 minutes to obtain a solution. Slowly introducing ammonia until the reaction solution is clear and reaches constant weight, then reacting at constant temperature for 2-4 hours, and then refluxing for 2-4 hours to obtain an intermediate product. Spray the intermediate product solution into the reaction kettle, spray hydroxyethyl sulfonic acid at the same time, stir and mix to form a reaction system, react at constant temperature for 2-3 hours, then filter while it is hot, and spray the filtrate into the low-temperature reaction kettle to obtain fine powder.
3. Final treatment:
Filtering while it is hot, and spraying the filtrate into a low-temperature reaction kettle to obtain fine powder of hexamidine dihydroxyethyl sulfonate.
How and where to buy Hexamidine Diisethionate?
You can trust us completely because we have a good record in selling legal education drugs. Over the years, we have reached Many orders cooperation between Europe and America, which is safe and fast. Have safeguard.
Reasons for choosing us: reliable strength supply, high quality and stable storage, worry-free supply and timely delivery after sale.
Send your Inquiry for more details, Click email：sales7@faithfulbio.com Now.
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email:sales7@faithfulbio.com Now.
Disclaimer: The articles published on this website are mainly used for academic research and technical discussions, which is dialectical and does not mean that this website agrees with all of its views. Please carefully screen. If there is any infringement or other dispute, please contact the administrator. We are not responsible for the consequences of using the information and services on this website.
Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
Hot Tags: hexamidine diisethionate cas 659-40-5, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China