What is Deoxyribonucleic Acid Sodium Salt ?
Deoxyribonucleic Acid Sodium Salt is an indispensable basic substance in life science research and biotechnology industry. From basic academic exploration to cutting-edge gene therapy, its application runs through the whole field of modern biology and is the core tool for understanding and manipulating genetic information.
DNA Na is the sodium salt form of deoxyribonucleic acid, genomic (HY-109517). It is a double-stranded template DNA separated from DEOXYRIBONUCLEIC ACID SODIUM SALT, which can be used to study the interaction between DNA and DNA binding agent, the structure and function of DNA, and the substrate for DNA quantification and DNA polymerase analysis.
DNA: A biomacromolecule that carries the genetic information of all known living organisms.
Sodium salt: Deoxyribonucleic Acid Sodium Salt is a salt form formed in the process of DNA purification in order to neutralize its negative charge and increase its stability.
Simply put, most of the "purified DNA" or "reagent-grade DNA" that we usually come into contact with in the laboratory are in the form of this sodium salt.
Physical and chemical properties
Appearance: white or white-like fibrous or powdery solid.
Solubility: Soluble in water or buffer solution to form a viscous solution. Insoluble in organic solvents.
Stability: it can be stored stably for a long time under dry, dark and low temperature (such as-20 C). In aqueous solution, repeated freezing and thawing should be avoided and DNA enzyme pollution should be prevented.
| Product name | Deoxyribonucleic Acid Sodium Salt |
| CAS | 73049-39-5 |
| EINECS | 297-226-7 |
| Solubility | H2O: 1 mg/ml, slightly turbid, slightly yellow and sticky. |
| Water solubility | 1 mg/ml. |
| Storage condition | Sealed in dry,Room Temperature |
What are the functions of Deoxyribonucleic Acid Sodium Salt?
As the most stable common form of DNA, its function and application cover almost the whole field of modern life science and biotechnology. The following is a summary of its core functions and a detailed classification of specific applications.Its core function is as a carrier of genetic information and a template for biosynthesis. The specific performance is as follows:Its base sequence carries genetic instructions and can be used as a template for replication and transcription.Substrate of biochemical reaction: as the substrate of various enzymes.Biomaterials: Using their molecular recognition and self-assembly characteristics to construct nanostructures.
What are the main application fields of Deoxyribonucleic Acid Sodium Salt?
Main application fields
The following is a detailed classification according to the application scenarios:
First, basic molecular biology research
This is its most classic and extensive application field, and it is the "daily consumables" of the laboratory.
1.As a DNA template, specific fragments can be amplified to detect the existence of genes, perform genotyping or prepare a large amount of DNA.
Cloning experiment: connecting the target DNA fragment with the vector DNA, transforming it into bacteria, thus multiplying in large quantities.DNA sequencing: As a sequencing template, Deoxyribonucleic Acid Sodium Salt is used to determine its accurate base sequence.
2. Biotechnology and Pharmacy
Production of recombinant protein: The gene encoding a specific protein is inserted into an expression vector and transfected into a host cell to produce protein with therapeutic value on a large scale.Gene therapy and DNA vaccine;Gene therapy: introducing normal genes into patients to replace or correct defective genes for the treatment of hereditary diseases or cancer.
3. functional materials and nanotechnology
This is a new frontier field, using the excellent engineering characteristics of DNA molecules.DNA nanotechnology: Self-assembly of pre-designed and fine two-dimensional or three-dimensional nanostructures like Lego based on the principle of complementary base pairing of DNA, which is used in drug delivery, biosensing and materials science.
Product Specification
| Items | Specifications | Results |
|
Appearance |
White powder | White powder |
| Purity | ≥98.0% min | 98.16% |
| Loss on Drying | ≤ 0.50% | Complies |
| Residue on Ignition | ≤ 0.10% | Complies |
|
Heavy Metals |
≤20ppm |
<20ppm |
|
Clarity Of Solution |
Conform To Standard |
Complies |
|
Microbial Limit |
≤20ppm |
<20ppm |
| Conclusion: The test results are conformed to the in-house specification | ||
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FAQ:
Q1:Why is Deoxyribonucleic Acid Sodium Salt usually "sodium salt" and not other salts ?
A1:Sodium salt is the most common and economical choice. In the standard DNA purification process, a solution containing sodium ions is used. Sodium ions can efficiently neutralize the negative charge of DNA and precipitate it from the solution. Other salt forms also exist, which may have different efficiency in some specific applications, but sodium salt is the general standard.
Q2: What is its main source?
A2: 1. Calf thymus: a traditional and common source, which can extract high molecular weight DNA and is often used in basic research and as a biochemical reagent. 2. Recombinant microorganisms: mass production by fermentation technology is the main source of modern biopharmaceuticals and molecular biological reagents.
Q3: How do you set the price,Can I get a better price ?
A3: The price is negotiable! As long as the quantity you ordered is large enough, we can definitely give you a more satisfactory price. Is it convenient for you to tell us the approximate demand quantity? So I can prepare a more accurate quotation for you.
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Attention: It should be noted that this product is not intended for the diagnosis, treatment, cure, or prevention of any disease. Please consult your doctor and learn about available research before use. Please do not use without authorization. This compound can only be used for research purposes. The US Food and Drug Administration has not evaluated these claims.
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