Product description
Neomycin Sulfate Powder is an aminoglycoside antibiotic. The product has good antibacterial action against enterobacteriaceae bacteria such as Staphylococcus (methicillin-sensitive strains), Corynebacterium, Escherichia coli, Klebsiella, Proteus, etc., but poor activity against streptococcus, Streptococcus pneumoniae and Enterococcus in each group. Pseudomonas aeruginosa, anaerobic bacteria and other drug resistant to this product. The bacteria had partial or complete cross-resistance to streptomycin, neomycin, kanamycin and gentamicin.
Neomycin sulfate is an antibiotic used to reduce the risk of infection during surgery of the bowel. Neomycin is also used to reduce the symptoms of hepatic coma. Neomycin sulfate is available in generic form.
Neomycin Sulfate Powder is the sulfate salt form of neomycin, a broad spectrum aminoglycoside antibiotic derived from Streptomyces fradiae with antibacterial activity. Neomycin is an antibiotic complex consisting of 3 components: the two isomeric components B and C are the active components, and neomycin A is the minor component. Neomycin irreversibly binds to the 16S rRNA and S12 protein of the bacterial 30S ribosomal subunit. As a result, this agent interferes with the assembly of initiation complex between mRNA and the bacterial ribosome, thereby inhibiting the initiation of protein synthesis. In addition, neomycin induces misreading of the mRNA template and causes translational frameshift, thereby results in premature termination. This eventually leads to bacterial cell death.
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COA
| ltems | Standard | Results |
| Appearance | A white or yellowish-white powder. Odorless or almost. Hygroscopic | Complies |
| Identification | A;B;C The positive reaction. | Complies |
| Solubility | Very soluble in water,insoluble in acetone,chloroform,ether. | Complies |
| Impurity A | ≤2% | Complies |
| Impurity C | 3%-15% | Complies |
| Specific optical rotation | +53.5°to +59.0° | +58.2° |
| Acidity or alkalinity(PH) | 5.0-7.5 | 6.5 |
| Loss on drying | ≤8.0% | 4.50% |
| Assay(Microbial) | ≥600μg/mg(DRY) | 672μg/mg(DRY) |
| 637μg/mg(MOIST) | ||
| Conclusion： | The product meets the requirements of USP29. | |
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What is neomycin sulfate used for?
Neomycin Sulfate Powder is primarily used to treat and manage hepatic coma and perioperative prophylaxis. Neomycin belongs to the aminoglycosides group of antibiotics, which functions by inhibiting bacterial protein synthesis, resulting in a bactericidal effect primarily against gram-negative bacteria.
Is neomycin sulfate good for skin?
Neomycin, an antibiotic, is used to prevent or treat skin infections caused by bacteria. It is not effective against fungal or viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Is neomycin sulfate bad?
Serious side effects, such as damage to hearing, sense of balance, and kidneys may occur in elderly patients, who are usually more sensitive than younger adults to the effects of neomycin.
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why choose us
Our Factory
Package
Shipping Methods
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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