What is Ebselen?
Xi'an Faithful BioTech Co., Ltd. is situated in Xi'an, the birthplace of the ancient Silk Road. Leveraging the city's mature logistics network and abundant fine chemical industrial resources, our enterprise has grown into an integrated fine chemical provider that delivers products to global partners. Ebselen, CAS No. 60940-34-3, molecular formula C₁₃H₉NOSe, molecular weight 274.18, is a synthetic organoselenium small molecule raw material with a special selenium heterocyclic structure. It appears as a light yellow to off-white needle-like crystalline powder with a melting point range of 176 to 182 degrees Celsius. It is stable in physicochemical properties under normal temperature and light protection conditions and is almost insoluble in pure water. It is recommended to store it in a low-temperature and light-protected environment to delay the darkening of its color. The most core biological characteristic of this substance is that it mimics the function of glutathione peroxidase, which can efficiently remove excess reactive oxygen species, lipid peroxides and peroxynitrite in the system, block free radical chain oxidation reactions, and inhibit cyclooxygenase, lipoxygenase and multiple inflammatory regulatory pathways, thus achieving dual biological effects of antioxidation and anti-inflammation. Its small molecular size allows it to penetrate multiple biological barriers and act on various tissue cells such as nerves, auditory epithelium, cardiovascular system, liver and kidneys, alleviate cell damage caused by oxidative imbalance, reduce tissue loss caused by external stimuli, and stabilize the intracellular redox signaling system.
Application of Ebselen
Ebselen, with its antioxidant, anti-inflammatory, and protease-regulating properties, is widely used in various biological research experiments. It can be used to construct oxidative stress cell models and explore the mechanisms of protection of nerve, auditory, and organ cells. It is also used for screening pathogenic microorganisms for inhibitory activity and verifying inflammatory pathways. It is a commonly used lead material in biochemical laboratories, with a wide safety range, and is suitable for basic research at multiple cell and tissue levels.
COA
| Test Item | Specification | Test Result |
| Appearance | Light yellow to off-white needle-like crystalline powder |
Complies |
| Molecular Formula | C1₃H₉NOSe | Complies |
| Molecular Weight | 274.18 | Complies |
| Melting Point | 176-182℃ | Complies |
| Solubility | Almost insoluble in water, soluble in DMSO,ethanol |
Complies |
| Purity(HPLC) | ≥98.0% | 98.52% |
| Loss on Drying | ≤0.5% | 0.21% |
| Residue on Ignition | ≤0.2% | 0.08% |
| Conclusion | Conform with enterprise specification | |
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Boiling point: 402.8±28.0 °C (Predicted)
Melting point: 176-182 °C
Molecular formula: C13H9NOSe
Molecular weight: 274.18
Flash point: 197.4±24.0 °C
Exact mass: 274.984924 g
PSA: 22.00000
LogP: 2.04770
Ebselen's mechanism of action
Mimicking glutathione peroxidase activity: Clears reactive oxygen species and lipid peroxides, blocks free radical oxidation chain reactions, provides potent antioxidant effects, and alleviates oxidative stress damage.
Multiple anti-inflammatory regulatory mechanisms: Inhibits inflammation-related enzymes such as cyclooxygenase and lipoxygenase, blocks the NF-κB inflammatory pathway, and reduces tissue inflammation.
Targeting cysteine proteins: Binds to cysteine residues in proteins, regulates cellular redox signaling, and simultaneously inhibits pathogenic proteases, hindering pathogen proliferation.
Cross-barrier cellular protection: Small molecules easily penetrate biological barriers, acting on nerve, auditory, liver, kidney, and cardiovascular cells, stabilizing intracellular oxidative balance, and reducing cell damage caused by external stimuli.
why choose us
We adhere to the principle of "customer first, honesty first", and always provide customers with high-quality and efficient products and high-quality services. Choose faithfulness. Choose a healthy life!
With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.
Our Factory
Package
Shipping Methods
| Transportation Time | Shipping method | Cargo weight requirements | Advantage |
| 3-7 days | DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS |
Suitable for under 50kg. International door to door express |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
| 7-15 days | By Air | Suitable for more than 50kg. fast and cheaper for large order |
|
| 15-60 days | By Sea | Suitable for more than 500kg. Cheapest shipping way |
FAQ
01. Which enzyme does Ebselen mimic to achieve its antioxidant effect?
It mimics glutathione peroxidase.
02. What is the mechanism of Ebselen's antioxidant effect?
It eliminates excess reactive oxygen species and lipid peroxides in the body, interrupting the free radical oxidation chain reaction.
03. What are Ebselen's effects on microorganisms?
Ebselen can bind to cysteine proteases in pathogens, interfering with the pathogen's replication process.
Click email：Sales4@Faithfulbio.Com Or WhatsApp：+86 17782784907
Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.
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