2'-Deoxycytidine Monohydrate CAS 951-77-9
Product Name:2'-Deoxycytidine
CAS NO.: 951-77-9
Molecular Formula:C9H13N3O4
EINECS.NO:213-454-1
Synonym:2′-Deoxycytidine;2’-Deoxy Cytidine;2'-DEOXYCYTIDINE;2'-Deoxycytidine;2'-deoxy-Cytidine;2'-Deoxycytidine monohydrate
;2’-Deoxycytidine;2′-Deoxycytidine hydrochloride;Cytosine deoxyribonucleoside;Cytosine deoxyriboside;Deoxycytidine;Deoxyribose cytidine
Test Method:HPLC/UV
MOQ & Package: 10g,100g,1kg etc Sub-package
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life; Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany.
Description
2'-Deoxycytidine monohydrate is a white or yellow powder. As an important pharmaceutical intermediate, 2'-deoxyribocytidine is mostly used to synthesize monomers of deoxyribonucleotides and prepare oligodeoxyribonucleotides, which are widely used in nucleic acid and genetic engineering.
| structural formula |
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ITEMS |
SPECIFICATIONS |
RESULTS |
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Appearance |
White or yellowish powder |
Complies |
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Odor &Tasted |
Characteristic |
Complies |
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purity |
≥98% |
99.8 |
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Loss on Drying(%) |
≤0.5 |
0.14 |
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Residue on lgnition(%) |
≤0.1 |
0.02 |
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Particle size(%) |
100% through 80 mesh sieves |
100% |
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Heavy Metal(ppm) |
≤10.0 |
1.38 |
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Pb(ppm) |
≤1.0 |
Negative |
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As(ppm) |
≤1.0 |
Negative |
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Hg(ppm) |
≤0.1 |
Negative |
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Cd(ppm) |
≤1.0 |
0.0008 |
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Microbiological Tests |
Total Plate Count(cfu/g) |
≤1000 |
2.38 |
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Yeasts and Moulds(cfu/g) |
≤100 |
0.38 |
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E.coli(cfu/g) |
Negative |
Complies |
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Salmonella |
Negative |
Complies |
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Conclusion：Conform with enterprise specification . |
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What is the latest progress in the anti-cancer research of Deoxycytidine?
2'-Deoxycytidine may become a new product for cancer cell research in the future. The research group transplanted tumor subcutaneously into nude mice, and then use a certain amount of 2'-Deoxycytidine solvent. Through comparative experiments, it was found that 2'-Deoxycytidine inhibited the proliferation of cancer cell QBC939, the cell cycle was arrested in G1 phase, and the apoptosis increased. The above effects were positively correlated with the drug concentration and the time used. In addition, the research group used MTT method to detect the effects of 2'-Deoxycytidine monohydrate and other anti-tumor drugs on the survival rate of cholangiocarcinoma cell line QBC939, and used flow cytometry to observe the changes of cell growth cycle and apoptosis rate. Finally, it was found that the tumorigenesis rate of QBC939 decreased significantly in nude mice.
How to prepare high quality 2'- deoxycytidine?
2'- deoxycytidine is a multifunctional molecular biological probe for DNA/RNA incorporation, which has been involved in various molecular biological applications, such as gene expression, chromosome and mRNA fluorescence in situ hybridization (FISH) experiments, mutation detection on arrays and microarrays, in situ RT-PCR and PCR. In addition, this product has a wider range of biological applications. For example, in the research of bioengineering, 2'-Deoxycytidine monohydrate is a deoxyribonucleoside. As a regulator of Eg5 kinesin, it has anti-proliferation and apoptosis-inducing activities.Due to the special purpose of this product, it is necessary to strictly follow the following steps for its production.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide 2'-Deoxycytidine monohydrate powder etc. at a more favorable price. If you are interested, please leave a message.
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